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A Humidity-Sensitive Hydrogel-Bacillus Spore Composite For Micropatterning Of Biomolecular Gradients, Richard L. Gieseck, Bin-Da Chan, Cagri A. Savran
A Humidity-Sensitive Hydrogel-Bacillus Spore Composite For Micropatterning Of Biomolecular Gradients, Richard L. Gieseck, Bin-Da Chan, Cagri A. Savran
Birck and NCN Publications
A composite material consisting of Bacillus subtilis spores suspended in a humidity sensitive hydrogel can be used to pattern biomolecules in different concentrations directly onto glass surfaces using a mechanical micromanipulator. By altering the relative humidity surrounding the composite gel during deposition, surface concentration of patterned biomolecules can be controlled and varied to create user-defined, biomolecular surface concentrations. (C) 2013 AIP Publishing LLC.