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Full-Text Articles in Nanoscience and Nanotechnology
Au@Tio2 Nanocomposites Synthesized By X-Ray Radiolysis As Potential Radiosensitizers, Maria C. Molina Higgins
Au@Tio2 Nanocomposites Synthesized By X-Ray Radiolysis As Potential Radiosensitizers, Maria C. Molina Higgins
Theses and Dissertations
Radiosensitization is a novel targeted therapy strategy where chemical compounds are being explored to enhance the sensitivity of the tissue to the effects of ionizing radiation. Among the different radiosensitizers alternatives, nanomaterials have shown promising results by enhancing tumor injury through the production of free radicals and reactive oxygen species (ROS). In this work, Gold-supported titania (Au@TiO2) nanocomposites were synthesized through an innovative strategy using X-ray irradiation, and their potential as radiosensitizers was investigated. Radiosensitization of Au@TiO2 nanocomposites was assessed by monitoring the decomposition of Methylene Blue (MB) under X-ray irradiation in the presence of the nanomaterial. …
Lanthanide-Based Core-Shell Nanoparticles As Multifunctional Platforms For Targeted Radionuclide Therapy And Multimodal Molecular Imaging, Miguel Toro-Gonzalez
Lanthanide-Based Core-Shell Nanoparticles As Multifunctional Platforms For Targeted Radionuclide Therapy And Multimodal Molecular Imaging, Miguel Toro-Gonzalez
Theses and Dissertations
Lanthanide phosphate (LnPO4) and lanthanide vanadate (LnVO4) nanoparticles (NPs) are promising platforms for theranostic applications because of their chemical stability, low solubility, low toxicity, and unique luminescence and magnetic properties. Motivated by the high radiation resistance and ability to host actinides of naturally occurring lanthanide-based compounds, LnPO4 and LnVO4 NPs were studied as radionuclide carriers for targeted radionuclide therapy using in vivoα-generators, 223Ra, 225Ac, and 227Th. The implementation of these radionuclides has shown potential for the treatment of micrometastases and solid tumors as well as challenges in the retention of …
Electrostatic Discharge Properties Of Irradiated Nanocomposites, Joshua D. Mcgary
Electrostatic Discharge Properties Of Irradiated Nanocomposites, Joshua D. Mcgary
Theses and Dissertations
Modernization in space systems requires employment of new light-weight, high performance composite materials that reduce bulk weight and increase structural integrity. This thesis explored the behavior of one such material prior to and following a 35-year simulated space radiation life-cycle. Select electrical properties of nickel nanostrandTM-carbon composites in seven configurations were characterized prior to electron irradiation via surface and bulk resistivity measurements and contact electrostatic discharge (ESD) measurements. Following irradiation at a fluence of 1016 e-/cm2 at an average energy of 500 keV, measurements were repeated and compared against pre-irradiation data. Configuration D is …