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Full-Text Articles in Nanoscience and Nanotechnology

Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence Jan 2021

Nebulizer-Based Systems To Improve Pharmaceutical Aerosol Delivery To The Lungs, Benjamin M. Spence

Theses and Dissertations

Combining vibrating mesh nebulizers with additional new technologies leads to substantial improvements in pharmaceutical aerosol delivery to the lungs across therapeutic administration methods. In this dissertation, streamlined components, aerosol administration synchronization, and/or Excipient Enhanced Growth (EEG) technologies were utilized to develop and test several novel devices and aerosol delivery systems. The first focus of this work was to improve the poor delivery efficiency, e.g., 3.6% of nominal dose (Dugernier et al. 2017), of aerosolized medication administration to adult human subjects concurrent with high flow nasal cannula (HFNC) therapy, a form of continuous-flow non-invasive ventilation (NIV). The developed Low-Volume Mixer-Heater (LVMH) …


Electrostatic Discharge Properties Of Irradiated Nanocomposites, Joshua D. Mcgary Mar 2009

Electrostatic Discharge Properties Of Irradiated Nanocomposites, Joshua D. Mcgary

Theses and Dissertations

Modernization in space systems requires employment of new light-weight, high performance composite materials that reduce bulk weight and increase structural integrity. This thesis explored the behavior of one such material prior to and following a 35-year simulated space radiation life-cycle. Select electrical properties of nickel nanostrandTM-carbon composites in seven configurations were characterized prior to electron irradiation via surface and bulk resistivity measurements and contact electrostatic discharge (ESD) measurements. Following irradiation at a fluence of 1016 e-/cm2 at an average energy of 500 keV, measurements were repeated and compared against pre-irradiation data. Configuration D is …


Fatigue Evaluation Of Nanocomposites As Lightweight Electronic Enclosures For Satellites' Applications, Javier Rodriguez Mar 2009

Fatigue Evaluation Of Nanocomposites As Lightweight Electronic Enclosures For Satellites' Applications, Javier Rodriguez

Theses and Dissertations

Existing nanocomposite materials used for satellite applications don't offer the required conductivity and electromagnetic shielding protection, requiring metal shields in order to survive in space. The AFRL Materials and Manufacturing Directorate in conjunction with the private sector have developed a material that promises to blend the attributes of nanocomposites and metal materials. The M55J/RS3 material consists of carbon fibers combined with a polyisocyanate matrix, in which Nickel nanostrandsTM are added. The research effort investigated the changes in the EMI and ESD of the material after being subjected to cyclic loads. Four configurations of a symmetric layup with fibers oriented …


Evaluation Of Nanocomposites As Lightweight Electronic Enclosures For Satellites' Applications, Benjamin T. Harder Jun 2008

Evaluation Of Nanocomposites As Lightweight Electronic Enclosures For Satellites' Applications, Benjamin T. Harder

Theses and Dissertations

The United States military is exploring the use of nanocomposite materials for satellite structural applications. Current composite spacecraft structures are nonconductive and must have expensive shielding materials applied in order to protect the spacecraft from catastrophic damage that can be caused by electromagnetic interference (EMI) and/or electrostatic discharge (ESD) which are characteristics of the space environment. Conductive nanocomposites are being developed for spacecraft structures that will provide ESD and EMI shielding protection without the need for expensive secondary shielding materials. This thesis studied one such material consisting of M55J/RS-3 composite combined with nickel nanostrands™. Four different configurations were tested for …