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Full-Text Articles in Nanoscience and Nanotechnology
The Relationship Between Total Neuropathy Score-Reduced, Neuropathy Symptoms And Function., Ashraf Abulhaija
The Relationship Between Total Neuropathy Score-Reduced, Neuropathy Symptoms And Function., Ashraf Abulhaija
USF Tampa Graduate Theses and Dissertations
Chemotherapy Induced Peripheral Neuropathy (CIPN) is a common problem among cancer patients who receive a wide range of chemotherapy. This problem causes a decline in quality of life and increased disabilities. CIPN assessment instruments are either subjective, objective, or a combination of both. So far, there is no agreement on the best way for assessment. The goal of this study was to explore the relationships among subjective and objective CIPN assessment instruments. Specifically, this study aimed to 1) evaluate the relationship between the Total Neuropathy Score-reduced (mainly objective) and patients’ function, as measured by the interference scale of the Chemotherapy-Induced …
Bisphosphonate Functionalized Gold Nanoparticles For The Study And Treatment Of Osteoporotic Disease, Christopher Conners
Bisphosphonate Functionalized Gold Nanoparticles For The Study And Treatment Of Osteoporotic Disease, Christopher Conners
USF Tampa Graduate Theses and Dissertations
The use of nanoparticles for disease treatment is an increasingly popular area of research. The potential for multi-functionality allows nanoparticles to be used as transport and delivery vehicles for drugs and as diagnostic aides, among other applications, to address the unmet needs of many disease treatments. One such class of disease is osteoporosis including severe disorders, like Paget’s disease, Osteogenesis Imperfecta and Legg Calve Perthes disease. In this dissertation, we discuss a nanoparticle system consisting of gold nanoparticles surface functionalized with primary amine bisphosphonates, which is a classification of pharmaceuticals that is common in the treatment of osteoporosis. Functionalized nanoparticles …