Nanoscience and Nanotechnology Commons^™

Formulation And Characterization Of Raloxifene Nanostructured Lipid Carries For Permeability Enhancement Applications, Anju Sharma

USF Tampa Graduate Theses and Dissertations

Raloxifene (RLX), a BCS class-II drug is a selective estrogen receptor modulator (SERM)having estrogenic effect on bone and antiestrogenic effect on endometrium and breast respectively. Low solubility, high permeability, high metabolism and low bioavailability are the characteristics of raloxifene. It is used to prevent and treat in women and those on It is also used to reduce the risk of in those at high risk. Although 60% is absorbed orally, raloxifene shows extremely poor bioavailability (2%) owing to its low solubility and an extensive (>90%) intestinal/hepatic first-pass metabolism. Hence it becomes important to increase the solubility of raloxifene in …

Magneto-Dielectric Polymer Nanocomposite Engineered Substrate For Rf And Microwave Antennas, Cesar A. Morales

USF Tampa Graduate Theses and Dissertations

This dissertation presents the first reported systematic investigation on the implementation of multilayer patch antennas over Fe3O4-based polymer nanocomposite (PNC) magneto-dielectric substrates. The PNC substrate is created by the monodispersion of Fe3O4 nanopthesiss, with mean size of 7.5nm, in a polymeric matrix of Polydimethylsiloxane (PDMS).

Recently, magneto-dielectric substrates have been proposed by several researchers as a means for decreasing the size and increasing the bandwidth of planar antennas. Nevertheless, factors such as high loss and diminished control over magnetic and dielectric properties have hindered the optimal performance of antennas. In addition, the incompatibility and elevated complexity prevents integration of conventional …