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Full-Text Articles in Nanoscience and Nanotechnology
Imaging, Spectroscopic, Mechanical And Biocompatibility Studies Of Electrospun Tecoflex® Eg 80a Nanofibers And Composites Thereof Containing Multiwalled Carbon Nanotubes, Javier Macossay-Torres, Faheem A. Sheikh, Travis Cantu, Thomas Eubanks, M. Esther Salinas, Chakavak S. Farhangi, Hassan Ahmad, M. Shamshi Hassan, Myung-Seob Khil, Shivani K. Maffi, Hern Kim, Gary L. Bowlin
Imaging, Spectroscopic, Mechanical And Biocompatibility Studies Of Electrospun Tecoflex® Eg 80a Nanofibers And Composites Thereof Containing Multiwalled Carbon Nanotubes, Javier Macossay-Torres, Faheem A. Sheikh, Travis Cantu, Thomas Eubanks, M. Esther Salinas, Chakavak S. Farhangi, Hassan Ahmad, M. Shamshi Hassan, Myung-Seob Khil, Shivani K. Maffi, Hern Kim, Gary L. Bowlin
Chemistry Faculty Publications and Presentations
The present study discusses the design, development and characterization of electrospun Tecoflex® EG 80A class of polyurethane nanofibers and the incorporation of multiwalled carbon nanotubes (MWCNTs) to these materials. Scanning electron microscopy results confirmed the presence of polymer nanofibers, which showed a decrease in fiber diameter at 0.5% wt. and 1% wt. MWCNTs loadings, while transmission electron microscopy showed evidence of the MWCNTs embedded within the polymer matrix. The fourier transform infrared spectroscopy and Raman spectroscopy were used to elucidate the polymer-MWCNTs intermolecular interactions, indicating that the C-N and N-H bonds in polyurethanes are responsible for the interactions with MWCNTs. …
Biodegradable Electrospun Nanofibers Coated With Platelet-Rich Plasma For Cell Adhesion And Proliferation, Luis Diaz-Gomez, Carmen Alvarez-Lorenzo, Angel Concheiro, Maite Silva, Fernando Dominguez, Faheem A. Sheikh, Travis Cantu, Raj Desai, Vanessa L. Garcia, Javier Macossay-Torres
Biodegradable Electrospun Nanofibers Coated With Platelet-Rich Plasma For Cell Adhesion And Proliferation, Luis Diaz-Gomez, Carmen Alvarez-Lorenzo, Angel Concheiro, Maite Silva, Fernando Dominguez, Faheem A. Sheikh, Travis Cantu, Raj Desai, Vanessa L. Garcia, Javier Macossay-Torres
Chemistry Faculty Publications and Presentations
Biodegradable electrospun poly(ε-caprolactone) (PCL) scaffolds were coated with platelet-rich plasma (PRP) to improve cell adhesion and proliferation. PRP was obtained from human buffy coat, and tested on human adipose-derived mesenchymal stem cells (MSC) to confirm cell proliferation and cytocompatibility. Then, PRP was adsorbed on the PCL scaffolds via lyophilization, which resulted in uniform sponge-like coating of 2.85 (s.d. 0.14) mg/mg. The scaffolds were evaluated regarding mechanical properties (Young’s modulus, tensile stress and tensile strain), sustained release of total protein and growth factors (PDGF-BB, TGF-β1 and VEGF), and hemocompatibility. MSC seeded on the PRP-PCL nanofibers showed an increased adhesion and proliferation …