Open Access. Powered by Scholars. Published by Universities.®
Nanoscience and Nanotechnology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
- Keyword
-
- Alternating (1)
- Aluminum oxide; Nanostructures; Porous silicon; Thin films (1)
- Dielectrics (1)
- Electric currents (1)
- Electric double layer (1)
-
- Electric fields (1)
- Glioblastoma multiforme – Treatment (1)
- Gliomas – Treatment (1)
- Gold films (1)
- Gold nanoshells (1)
- Hydrodynamics (1)
- Lasers (1)
- Macrophages (1)
- Nanostructured materials (1)
- Nanostructures (1)
- Particles (1)
- Photothermal ablation (1)
- Raman effect (1)
- Superparamagnetic iron oxide nanoparticles (1)
- Publication
- Publication Type
Articles 1 - 4 of 4
Full-Text Articles in Nanoscience and Nanotechnology
Macrophages Loaded With Gold Nanoshells For Photothermal Ablation Of Glioma: An In Vitro Model, Amani Riad Makkouk
Macrophages Loaded With Gold Nanoshells For Photothermal Ablation Of Glioma: An In Vitro Model, Amani Riad Makkouk
UNLV Theses, Dissertations, Professional Papers, and Capstones
The current median survival of patients with glioblastoma multiforme (GBM), the most common type of glioma, remains at 14.6 months despite multimodal treatments (surgery, radiotherapy and chemotherapy). This research aims to study the feasibility of photothermal ablation of glioma using gold nanoshells that are heated upon laser irradiation at their resonance wavelength. The novelty of our approach lies in improving nanoshell tumor delivery by loading them in macrophages, which are known to be recruited to gliomas via tumor-released chemoattractive agents. Ferumoxides, superparamagnetic iron oxide (SPIO) nanoparticles, are needed as an additional macrophage load in order to visualize macrophage accumulation in …
Fabrication, Characterization And Simulation Of Non-Lithographic Nanostructures And Their Potential Applications, Neelanjan Bhattacharya
Fabrication, Characterization And Simulation Of Non-Lithographic Nanostructures And Their Potential Applications, Neelanjan Bhattacharya
UNLV Theses, Dissertations, Professional Papers, and Capstones
The dissertation describes the formation of porous silicon through the pores of porous alumina on a silicon substrate. Porous silicon, by itself, is inherently a non-uniform material that has non-uniform optical and electronic properties. In addition, it is also mechanically fragile material requiring careful material handling. The porous silicon fabricated through the nanosized pores of porous alumina are expected to mitigate these problems, thereby enhancing commercial viability of the device. The porous silicon as well the porous alumina have been synthesized through anodisation for various parameters and also various types of anodizing electrolytes. The porous silicon, so obtained have been …
On The Effect Of Hydrodynamic Slip On The Polarization Of A Nonconducting Spherical Particle In An Alternating Electric Field, Hui Zhao
Mechanical Engineering Faculty Research
The polarization of a charged, dielectric, spherical particle with a hydrodynamically slipping surface under the influence of a uniform alternating electric field is studied by solving the standard model (the Poisson–Nernst–Planck equations). The dipole moment characterizing the strength of the polarization is computed as a function of the double layer thickness, the electric field frequency, the particle’s surface charge, and the slip length. Our studies reveal that two processes contribute to the dipole moment: ion transport inside the double layer driven by the electric field and the particle’s electrophoretic motion. The hydrodynamic slip will simultaneously impact both processes. In the …
Giant Raman Enhancement On Nanoporous Gold Film By Conjugating With Nanoparticles For Single-Molecule Detection, Lihua Qian, Biswajit Das, Yan Li, Zhilin Yang
Giant Raman Enhancement On Nanoporous Gold Film By Conjugating With Nanoparticles For Single-Molecule Detection, Lihua Qian, Biswajit Das, Yan Li, Zhilin Yang
Electrical & Computer Engineering Faculty Research
Hot spots have the contradictively geometrical requirements for both the narrowest interstices to provide strong near-field coupling, and sufficient space to allow entrance of the analytes. Herein, a two-step method is employed to create hot spots within hybrid nanostructures, which consist of self-supported nanoporous gold films with the absorbed probes and subsequent nanoparticle conjugates without surface agents or mechanical motion. The molecules confined into 1 nm interstice exhibit 2.9 × 107 times enhancement in Raman scattering compared to pure nanoporous gold. Giant enhancement primarily results from strong near-field coupling between nanopore and nanoparticle, which is theoretically confirmed by finite-difference …