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Full-Text Articles in Nanoscience and Nanotechnology
Graphene As A Solid-State Ligand For Palladium Catalyzed Cross-Coupling Reactions, Yuan Yang
Graphene As A Solid-State Ligand For Palladium Catalyzed Cross-Coupling Reactions, Yuan Yang
Theses and Dissertations
Palladium-catalyzed carbon-carbon cross-coupling reactions have emerged a broadly useful, selective and widely applicable method to synthesize pharmaceutical active ingredients. As currently practiced in the pharmaceutical industry, homogeneous Pd catalysts are typically used in cross-coupling reactions. The rational development of heterogeneous catalysts for cross-coupling reactions is critical for overcoming the major drawbacks of homogeneous catalysis including difficulties in the separation, purification, and quality control process in drug production. In order to apply heterogeneous catalysis to flow reactors that may overcome this limitation, the catalyst must be strongly bound to a support, highly stable with respect to leaching, and highly active. While …
The Role Of Microenvironment Reagent Solubility On Reaction Kinetics Of 4-Nitrophenol Reduction, Michael P. Zeevi, Andrew Harrison, Christina Tang
The Role Of Microenvironment Reagent Solubility On Reaction Kinetics Of 4-Nitrophenol Reduction, Michael P. Zeevi, Andrew Harrison, Christina Tang
Undergraduate Research Posters
The Role of Microenvironment Reagent Solubility on Reaction Kinetics of 4-Nitrophenol Reduction
Michael Zeevi1 with Andrew Harrison1 and Christina Tang, PhD1
1Department of Chemical and Life Science Engineering, VCU School of Engineering
Introduction: Nanoparticles are of increasing interest due to their high surface area to volume ratio, as well as that they enable fine-tuning of the reaction microenvironment. Through flash nanoprecipitation, core-shell polymer nanoreactors were formed by directed self-assembly. Using the reduction of 4-nitrophenol as a model reduction reaction, we investigated the effect of reagent solubility in the nanoreactor microenvironment’s on nanoreactor kinetics.
Methods: The standard …