Mechanical Engineering Commons^™

Characterizing Mechanical Regulation Of Bone Metastatic Breast Cancer Cells, Boyuan Liu

Doctoral Dissertations

Breast cancer most frequently metastasizes to the skeleton. Bone metastatic cancer is incurable and induces wide-spread bone osteolysis, resulting in significant patient morbidity and mortality. Mechanical stimuli in the skeleton are an important microenvironmental parameter that modulates tumor formation, osteolysis, and tumor cell-bone cell signaling, but which mechanical signals are the most beneficial and the corresponding molecular mechanisms are unknown. This work focused on bone matrix deformation and interstitial fluid flow based on their well-known roles in bone remodeling and in primary breast cancer. The goal of our research was to establish a platform that could define the relationship between …

Application Of Physically Based Semi-Distributed Hec-Hms Model For Flow Simulation In Tributary Catchments Of Kaohsiung Area Taiwan, Fiaz Hussain, Ray-Shyan Wu, Kai-Chun Yu

Journal of Marine Science and Technology

Hydrologic modeling is a commonly used tool to understand the rainfallerunoff processes of gauged and ungauged catchments for proper quantitative estimation of water resources availability. In the present study, an attempt is made to simulate surface runoff using a physically based semi-distributed hydrological (HEC-HMS) model for four local-scale tributary catchments of Kaohsiung area Taiwan. The input physical parameters of the model were calculated and preprocessed in HEC-GeoHMS based on digital elevation model (DEM), land use, soil and hydro-meteorological data. The model performance was satisfactory with Nash Sutcliffe Efficiency (NSE) ¼ 0.51 to 0.86 and the coefficient of determination (R2) ¼ …

The Development Of A Prosthetic Training Software For Upper Limb Amputees, Tyler Kayne Sullins

USF Tampa Graduate Theses and Dissertations

The purpose of this study was to develop an intuitive software that aids in the field of prosthetic training and rehabilitation by creating an individualized visualization of joint angles. This software is titled “the prosthetic training software (PTS) for individualized joint angle representation”, and it enables the individualized portrayal of predicted or pre-recorded joint angles. The PTS is an intuitive program for clinicians and prosthesis users that produces an animation of a virtual avatar reflecting the user’s segment lengths and amputation for rehabilitation and training purposes.

The PTS consists of a graphical user interface (GUI) and a 3D visualization of …

Simulation And Validation Of Radio Frequency Heating Of Shell Eggs, Soon Kiat Lau

Department of Food Science and Technology: Dissertations, Theses, and Student Research

Finite element models were developed with the purpose of finding an optimal radio frequency (RF) heating setup for pasteurizing shell eggs. Material properties of the yolk, albumen, and shell were measured and fitted into equations that were used as inputs for the model. When the egg was heated by itself, heating tend to be focused at the air cell to result in a “coagulation ring.” The focused heating near the air cell of the egg prevented satisfactory pasteurization of the egg, but deeper analysis of the simulation results offered a new perspective on how non-uniform RF heating could occur in …