Mechanical Engineering Commons^™

Validation Of A Two-Dimensional Clinostat Design To Provide Functional Weightlessness To Custom Gas Exchange Vessels, Collin R. Topolski

Doctoral Dissertations and Master's Theses

Understanding the impacts of microgravity on bacteria is vital for successful long duration space missions. In this environment, bacteria have been shown to become more virulent, more resistant to antibiotics and form more biofilms. To learn more about these phenomena, many experiments must be sent to the International Space Station, which is cost- and time prohibitive. Instead, the use of ground-based analogs is advantageous to define preliminary results that can later be verified with a space-based experiment. This research explored the development of an innovative 2D clinostat for simulating microgravity using bacteria. Computational fluid dynamics, standards established by previous literature …