Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 2 of 2
Full-Text Articles in Mechanical Engineering
Using Cfd To Improve Off-Design Throughflow Analysis, Troy J. Lanchman
Using Cfd To Improve Off-Design Throughflow Analysis, Troy J. Lanchman
Browse all Theses and Dissertations
In turbomachinery design, complex internal flows give rise to significant losses and blockage whose effects are difficult to properly analyze without detailed computational fluid dynamics (CFD) methods or experiments. In a typical design method, CFD is used in conjunction with simpler throughflow or cascade codes to hasten the process. However, the lesser physical accuracy of the design codes demands the inclusion of models to improve the accuracy of the throughflow codes. This thesis aims to use CFD data to generate improved loss and blockage models for a 2D compressor throughflow code by matching throughflow data to CFD data using optimizations. …
Design Of A Novel Tissue Culture System To Subject Aortic Tissue To Multidirectional Bicuspid Aortic Valve Wall Shear Stress, Janet Liu
Browse all Theses and Dissertations
Blood vessels experience complex hemodynamics marked by three-dimensionality and pulsatility. Arterial endothelial cells interact with the characteristics of the fluid wall shear stress (WSS) to maintain homeostasis or promote disease states. In particular, the bicuspid aortic valve (BAV), a congenital heart valve anatomy consisting of two leaflets instead of three, is associated with aortic complications presumably promoted by hemodynamic abnormalities. While devices have been used to test this hypothesis, their capabilities are limited to the generation of time-varying WSS magnitude in one direction. However, the increased flow helicity generated by BAVs in the aorta is expected to result in increased …