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Full-Text Articles in Mechanical Engineering
The Influence Of Flow Mechanotransduction On Endothelial Cells In The Lymphatic Valve Sinus, Joshua Daniel Hall
The Influence Of Flow Mechanotransduction On Endothelial Cells In The Lymphatic Valve Sinus, Joshua Daniel Hall
Doctoral Dissertations
Fluid flow in the cardiovascular and lymphatic systems influences the phenotype of endothelial cells that line the interior to the vessel via mechanotransduction. Geometric features in a vessel such as curvature, bifurcation, and valves promote heterogeneous fluid flow profiles, inducing a heterogeneous endothelial phenotype within a vessel region. Certain flow conditions are associated with vascular dysfunction, and diseases such as atherosclerosis preferentially develop in areas of flow disturbance. Lymphatic vessels are highly analogous to blood vessels, although lymphatic flow characteristics and its effect on lymphatic endothelial cells (LECs) via mechanotransduction have been comparatively less examined. The most significant geometric features …
Manual Material Handling Lift-Assist System For Occupational Exoskeleton, Erik Goes, Daniel Guthrie, Trevor Ward
Manual Material Handling Lift-Assist System For Occupational Exoskeleton, Erik Goes, Daniel Guthrie, Trevor Ward
Honors Capstones
It is no secret that lifting heavy objects is one of the premier causes of workplace injury, and the modern worker needs help to remain healthy. Workers need something they always have with them that makes their work safer as well as easier; our solution is an active lift-assist exoskeleton. The proposed exoskeleton design includes a military backpack exoskeleton frame, on which two actuators pull cables attached to end effectors that the operator will be holding. This system can adjust to conform to a wide variety of operator sizes, without restricting any of their range of motion. This leads to …