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Full-Text Articles in Mechanical Engineering
A Multi-Scale Cfd Analysis Of Patient-Specific Geometries To Tailor Lvad Cannula Implantation Under Pulsatile Flow Conditions: An Investigation Aimed At Reducing Stroke Incidence In Lvads, Ray Prather
Electronic Theses and Dissertations
A Left Ventricular Assist Device (LVAD) is a mechanical pump that provides temporary circulatory support when used as bridge-to-transplantation and relieves workload demand placed on a failing heart allowing for myocardia recovery when used as destination therapy. Stroke is the most devastating complication after ventricular assist device (VAD) implantation, with an incidence of 14-47% over 3-6 months. This complication due to thrombus formation and subsequent transport through the vasculature to cerebral vessels continues to limit the widespread implementation of VAD therapy. Patient-specific computational fluid dynamics (CFD) analysis may elucidate ways to reduce this risk. We employed a multi-scale model of …