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USF Tampa Graduate Theses and Dissertations

2018

Microfluidics

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Simulation And Optimization Of A Sheathless Size-Based Acoustic Particle Separator, Shivaraman Asoda Nov 2018

Simulation And Optimization Of A Sheathless Size-Based Acoustic Particle Separator, Shivaraman Asoda

USF Tampa Graduate Theses and Dissertations

Standing surface acoustic waves (SSAW) have been widely used for sorting of cells and particles. However, the major challenges faced with the acoustic driven separation process is the need for an optimized setup to achieve effective separation and the range of particles that can be separated. In this thesis, a custom simulation model is studied to investigate and optimize the separation of varying size particles in a sheathless acoustic separation platform that was developed in our research lab. Specifically, the effect of flowrate, pressure amplitude, wavelength and interdigitated transducers (IDTs) physical parameters on the separation efficiency is explored. We also …