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Mechanical Engineering Commons

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Electronic Theses and Dissertations

2012

Bench top

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A Bench Top Study Of The Optimization Of Lvad Cannula Implantation To Reduce Risk Of Cerebral Embolism, William D. Clark Jan 2012

A Bench Top Study Of The Optimization Of Lvad Cannula Implantation To Reduce Risk Of Cerebral Embolism, William D. Clark

Electronic Theses and Dissertations

Physical bench top experiments are performed to validate and complement ongoing computational fluid dynamics (CFD) analyses of ventricular assist device (VAD) circulation. VADs are used in patients whose hearts do not function to their maximum potential due advanced stages of heart disease and, consequently, are unable to adequately supply blood to the systemic circulation. VADs are commonly utilized as a bridge-to-transplantation, meaning that they are implanted in patients while waiting for a heart transplant. In such cases of long term utilization of VADs, it has been reported in the literatures that thrombo-embolic cerebral events occur in 14-47% of patients over …