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Articles 1 - 7 of 7
Full-Text Articles in Mechanical Engineering
Aging Effects On Arterial Mechanics And Matrix Remodeling, Jie Hawes
Aging Effects On Arterial Mechanics And Matrix Remodeling, Jie Hawes
McKelvey School of Engineering Theses & Dissertations
Large elastic arteries are a composite structure composed of cells and extracellular matrix proteins. Passive arterial mechanical behavior is determined by the composition of extracellular matrix proteins, in particular elastin and collagen. Elastin provides reversible elasticity to the large elastic arteries during cyclic loading and dampens the pulsatile flow from the left ventricle, reducing the workload on the heart and protecting the end organs. Disorganization and insufficiency of elastin alters the passive mechanical behavior of the large arteries. The arterial wall responds to changes in elastin organization or amount through matrix remodeling. Aging causes elastin fragmentation and degradation which changes …
New Modeling Approaches For The Prediction Of Combustion Pollutants, Phillip R. Johnson
New Modeling Approaches For The Prediction Of Combustion Pollutants, Phillip R. Johnson
McKelvey School of Engineering Theses & Dissertations
Combustion processes are ubiquitous to human technological development and provide many benefits such as large-scale power generation for electricity and transportation along with residential and commercial heating for manufacturing, cooking, and warmth. However, these various processes can also have harmful effects on human health and the environment via emission of CO2 and other pollutants such as NOx and particulate matter (PM; often in the form of soot). For these reasons, there is a continued need for controlling, improving, and optimizing combustion processes. Modeling of these processes provides powerful insights into system-level dynamics and their control. Due to the size and …
Exploring Attacks And Defenses In Additive Manufacturing Processes: Implications In Cyber-Physical Security, Nicholas Deily
Exploring Attacks And Defenses In Additive Manufacturing Processes: Implications In Cyber-Physical Security, Nicholas Deily
McKelvey School of Engineering Theses & Dissertations
Many industries are rapidly adopting additive manufacturing (AM) because of the added versatility this technology offers over traditional manufacturing techniques. But with AM, there comes a unique set of security challenges that must be addressed. In particular, the issue of part verification is critically important given the growing reliance of safety-critical systems on 3D printed parts. In this thesis, the current state of part verification technologies will be examined in the con- text of AM-specific geometric-modification attacks, and an automated tool for 3D printed part verification will be presented. This work will cover: 1) the impacts of malicious attacks on …
Development And Application Of Elliptic Blending Lag K-Omega Sst Standard And Wall-Distance-Free Turbulence Model, Wenjie Shang
Development And Application Of Elliptic Blending Lag K-Omega Sst Standard And Wall-Distance-Free Turbulence Model, Wenjie Shang
McKelvey School of Engineering Theses & Dissertations
In recent decades, Computational Fluid Dynamics (CFD) has become the most widely used technology to understand the fundamental complex fluid dynamics of turbulent flows as well as for modeling of turbulent flows in industrial applications. In industrial applications, the widely used methodology is to solve Reynolds-Average Navier-Stokes Equations (RANS) equations in conjunction with a turbulence model since it strikes a balance between accuracy and computational cost compared to other high fidelity approaches namely the Large Eddy Simulation (LES) and Direct Numerical Simulation (DNS), There are a large number of turbulence models proposed in past five decades, majority of them are …
Blood Flow Simulation Of Particle Trapping In Models Of Arterial Bifurcations, Qihang Xu
Blood Flow Simulation Of Particle Trapping In Models Of Arterial Bifurcations, Qihang Xu
McKelvey School of Engineering Theses & Dissertations
This thesis describes the particle trapping mechanism in blood flow in different arterial bifurcation models. For validation of CFD calculations, a T-junction model and a Y-junction model are analyzed. In both the models, there is one inlet pipe with two outlet pipes creating a symmetric bifurcation at some angle from the centerline of the inlet pipe. Naiver-Stokes (RANS) equations are solved for single phase laminar flow using the commercial CFD software ANSYS Fluent. After validation, Eulerian simulations are performed by using the Discrete Phase Model (DPM) for two-phase flow with particles injected in different bifurcation models with bifurcation angle of …
Design And Validation Of A Dynamic Pressure-Based Loading Device And 3d Strain Tracking Protocol For Ventral Hernia Modeling, Griffin Kivitz
Design And Validation Of A Dynamic Pressure-Based Loading Device And 3d Strain Tracking Protocol For Ventral Hernia Modeling, Griffin Kivitz
McKelvey School of Engineering Theses & Dissertations
It is estimated that 350,000-500,000 ventral hernia repair surgeries are performed each year in the United States. While the long-term recurrence rate of ventral hernia repairs is not yet known, when tissues are exposed to the trauma of surgery, there is always the chance of recurrence. Commonly used ex vivo testing methods for determining the mechanical properties of the abdominal wall and biomaterials for hernia repair consist primarily of uniaxial and biaxial testing, which are not physiologically relevant loading environments. The need for a testing device that can exert physiologically relevant loads ex vivo to an abdominal wall is crucial …
Hemodynamic Effects On Aortic Development Due To Outflow Tract Banding, Humza Ismail
Hemodynamic Effects On Aortic Development Due To Outflow Tract Banding, Humza Ismail
McKelvey School of Engineering Theses & Dissertations
Hemodynamic forces drive remodeling of the early cardiac system in embryonic development. Perturbations of normal cardiac blood flow can cause the formation of defects and malformations within the cardiac system. Specifically, changes in hemodynamics can cause the formation of different congenital heart defects. The formation of heart defects has been studied; however, vasculature specific defects caused by changes in blood flow patterns in the early cardiac system have not been studied to the same degree. In this thesis, the effects of hemodynamic changes on arterial development were studied. Outflow tract banding (OTB) was used to cause a local increase in …