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Mechanical Engineering Commons

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SelectedWorks

2015

Biomaterials

Articles 1 - 2 of 2

Full-Text Articles in Mechanical Engineering

Characterization Of Nickel-Doped Biphasic Calcium Phosphate/Graphene Nanoplatelet Composites For Biomedical Application Apr 2015

Characterization Of Nickel-Doped Biphasic Calcium Phosphate/Graphene Nanoplatelet Composites For Biomedical Application

Faculty of Engineering University of Malaya

The effect of the addition of an ionic dopant to calcium phosphates for biomedical applications requires specific research due to the essential roles played in such processes. In the present study, the mechanical and biological properties of Ni-doped hydroxyapatite (HA) and Ni-doped HA mixed with graphene nanoplatelets (GNPs) were evaluated. Ni (3 wt.% and 6 wt.%)-doped HA was synthesized using a continuous precipitation method and calcined at 900 degrees C for 1 h. The GNP (0.5-2 wt.%)-reinforced 6% Ni-doped HA (Ni6) composite was prepared using rotary ball milling for 15 h. The sintering process was performed using hot isostatic pressing …


Fabrication And Characterization Of Poly(Octanediol Citrate)/Gallium-Containing Bioglass Microcomposite Scaffolds Mar 2015

Fabrication And Characterization Of Poly(Octanediol Citrate)/Gallium-Containing Bioglass Microcomposite Scaffolds

Faculty of Engineering University of Malaya

Bone can be affected by osteosarcomae requiring surgical excision of the tumor as part of the treatment regime. Complete removal of cancerous cells is difficult and conventionally requires the removal of a margin of safety around the tumor to offer improved patient prognosis. This work considers a novel series of composite scaffolds based on poly(octanediol citrate) (POC) impregnated with gallium-based bioglass microparticles for possible incorporation into bone following tumor removal. The objective of this research was to fabricate and characterize these scaffolds and subsequently report on their mechanical and biological properties. The porous microcomposite scaffolds with various concentrations of bioglass …