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Mechanical Engineering Commons

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Full-Text Articles in Mechanical Engineering

Articular Cartilage Mechanical And Biochemical Property Relations Before And After In Vitro Growth, Timothy Ficklin, Gregory Thomas, James C. Barthel, Anna Asanbaeva, Eugene J. Thonar, Koichi Masuda, Albert C. Chen, Robert L. Sah, Andrew Davol, Stephen M. Klisch Jul 2007

Articular Cartilage Mechanical And Biochemical Property Relations Before And After In Vitro Growth, Timothy Ficklin, Gregory Thomas, James C. Barthel, Anna Asanbaeva, Eugene J. Thonar, Koichi Masuda, Albert C. Chen, Robert L. Sah, Andrew Davol, Stephen M. Klisch

Mechanical Engineering

The aim of this study was to design in vitro growth protocols that can comprehensively quantify articular cartilage structure–function relations via measurement of mechanical and biochemical properties. Newborn bovine patellofemoral groove articular cartilage explants were tested sequentially in confined compression (CC), unconfined compression (UCC), and torsional shear before (D0, i.e. day zero) and after (D14, i.e. day 14) unstimulated in vitro growth. The contents of collagen (COL), collagen-specific pyridinoline (PYR) crosslinks, glycosaminoglycan, and DNA significantly decreased during in vitro growth; consequently, a wide range of biochemical properties existed for investigating structure–function relations when pooling the D0 and D14 groups. All …


Regional Mechanical Properties And Stress Analysis Of The Human Anterior Lens Capsule, Ryan M. Pedrigi, G. David, J. Dziezyc, J. D. Humphrey Jan 2007

Regional Mechanical Properties And Stress Analysis Of The Human Anterior Lens Capsule, Ryan M. Pedrigi, G. David, J. Dziezyc, J. D. Humphrey

Department of Mechanical and Materials Engineering: Faculty Publications

The lens capsule of the eye functions, in part, as a deformable support through which the ciliary body applies tractions that can alter lens curvature and corresponding refractive power during the process of accommodation. Although it has long been recognized that characterization of the mechanical properties of the lens capsule is fundamental to understanding this physiologic process as well as clinical interventions, prior data have been limited by one-dimensional testing of excised specimens despite the existence of multiaxial loading in vivo. In this paper, we employ a novel experimental approach to study in situ the regional, multiaxial mechanical behavior of …


Measuring Skeletal Kinematics With Accelerometers On The Skin Surface, Kevin Curtis Ayer Jan 2007

Measuring Skeletal Kinematics With Accelerometers On The Skin Surface, Kevin Curtis Ayer

LSU Master's Theses

The most common motion analysis method uses cameras to track the position of markers on bodily surfaces over time. Although each species has a common skeletal frame to reference recorded motions, the soft tissue covering each is not rigid. Markers, therefore, experience motion relative to the bone and do not accurately portray underlying bone activity. This limits clinical use of motion studies and the understanding of joint motion. Use of MEMS accelerometers for removing soft tissue artifact, motion relative to the bone, from surface measurements and determining the position of the underlying bone was investigated. An animal limb was modeled …