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Full-Text Articles in Mechanical Engineering
Design Of A Microfabricated Device For Ligase Detection Reaction (Ldr), Dwhyte Omar Barrett
Design Of A Microfabricated Device For Ligase Detection Reaction (Ldr), Dwhyte Omar Barrett
LSU Master's Theses
The Ligase Detection Reaction (LDR) is a mutation detection technique used to identify point mutations in deoxyribonucleic acid (DNA). Developed by Francis Barany and associates at Cornell University it is used to find specific low abundant point mutations that may lead to colorectal cancer in the early stages of disease development. The research objective was to design and manufacture a microscale Ligase Detection Reaction (LDR) device in polycarbonate. The LDR module will be incorporated with other microdevices such as: Continuous Flow Polymerase Chain Reaction (CFRCR) and Capillary Electrophoresis (CE) in modular lab-on-a-chip technology. In making the microdevice, the duration of …
Ultra Deep Su-8 Manufacturing And Characterization For Mems Applications, Charles Joseph Becnel
Ultra Deep Su-8 Manufacturing And Characterization For Mems Applications, Charles Joseph Becnel
LSU Master's Theses
The Micro Systems Engineering Team (mSET) at Louisiana State University (LSU) utilizes microfabrication for a number of heat and mass transfer devices. These include cross flow heat exchangers, mechanical seals with integrated micro heat exchangers, catalytic converters, and micro reactors. In all of these applications, micro honeycomb arrays provide increased surface area per unit volume which significantly enhances heat and mass transfer. In the past, it was only possible to fabricate SU-8 structures approximately 1.5 mm tall. Furthermore, qualitatively, it is much more difficult to fabricate close packed feature arrays than sparse arrays. For many of the previously mentioned applications, …