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Full-Text Articles in Mechanical Engineering
3-D Silk Fibroin Porous Particles Created By The Ouzo Effect For Biomedical Applications, Ashley Nicole Lamb
3-D Silk Fibroin Porous Particles Created By The Ouzo Effect For Biomedical Applications, Ashley Nicole Lamb
UNLV Theses, Dissertations, Professional Papers, and Capstones
Due to its high biocompatibility and biodegradability, silk fibroin – produced from
Bombyx mori (B. mori) cocoons – has been at the forefront of research for many
biomedical application formats: hydrogels, films, microspheres, and porous
sponges/scaffolding, to name a few. For drug delivery, in particular, porous particles are
desirable for their large surface area, uniform and tunable pore structure, and high
porosity. This thesis focuses on the fabrication of porous particles from silk fibroin by the
very interesting Ouzo effect. The Ouzo effect, so named because of the Greek
beverage ouzo, describes the phenomenon of an ethanol + anethole oil …
Biodegradable And Biocompatible Silk Fibroin For Optical Applications, Corey Bryce Malinowski
Biodegradable And Biocompatible Silk Fibroin For Optical Applications, Corey Bryce Malinowski
UNLV Theses, Dissertations, Professional Papers, and Capstones
This study presents nanopatterned silk fibroin films that were fabricated using soft lithography and nanoimprinting to replicate patterns from diffraction gratings. These film’s optics were analyzed based on their light scattering potential as well as their transmittance and transmission haze using a laser light, spectrometer, and UV-Vis spectrophotometer, respectively. The patterned fibroin films all displayed similar light scattering patterns to their master patterns with some transmission haze. When using the spectrometer to measure samples, those made without any nanostructure displayed transmission of 90% and over, while those with patterns depended on the structure used. The denser a structure, like the …