Mechanical Engineering Commons^™

Liposomal Uptake Of Silver And Gold Nanoparticles, Dipon Chanda

LSU Master's Theses

The main objective of this work is to study the liposomal uptake of silver and old nanoparticles. Liposomes were prepared in Heating Method. The phospholipids used to prepare liposomes are 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (16:0 PC); 1,2-dipalmitoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 PG); 1,2-distearoyl-sn-glycero-3-phosphocholine (18:0 PC); 1,2-distearoyl-sn-glycero-3-phospho-(1'-rac-glycerol) (sodium salt) (18:0 PG).Four different combinations of phospholipids were used to prepare liposomes. In all four combinations two types of phospholipids were used. The liposomes were incubated for 30 minute, 1 hour, 2 hour and 4 hour with silver and gold nanoparticles in streptavidin coated glass slide. All four liposomal formulations had a biotinylated lipid (1-oleoyl-2-[12-biotinyl(aminododecanoyl)]-sn-glycero-3-phosphocholine) which has a string …