Mechanical Engineering Commons^™

A Multi-Aerial Vehicle Platform For Testing Collaborative Mobility Formation Controllers, Matthew Snellgrove

LSU Master's Theses

Multi-agent systems have potential applications in a multitude of fields due to their ability to perform complex tasks with a high degree of robustness. Decentralized systems are multi-agent systems where sensing, control, and communication responsibilities are distributed amongst the agents giving this scheme a particularly high potential for robustness, adaptability, and complexity; however, this comes with its own list of challenges. Formation control is a topic in multi-agent systems that aims to have the agents moving as a virtual rigid body through space. In the literature, there have been successful implementation of formation control algorithms on robot agents in both …

A Feedback-Based Pneumatic Compression System For Effective Lymphedema Management, Mohammad Imrul Kayes

LSU Master's Theses

Bioimpedance analysis (BIA) is a method of detecting lymphedema- a debilitating medical condition involving swelling of the extremities. Pneumatic compression devices are frequently used in the compression treatment of lymphedema. Although existing compression technology provides relief of symptoms, it has limitations in terms of ease-of-use, portability, and monitoring of treatment progress. Currently, there are no BIA analyzers in the market that run on a low-power microcontroller and a rechargeable battery. Moreover, no such device currently exists that integrate the BIA analysis with pneumatic compression system to offer a feedback-based solution for lymphedema treatment. This work represents the first steps towards …

Study On The Chemical And Mechanical Stability Of Polymer Nanofluidic Biosensors, Dae Won Kim

LSU Master's Theses

Polymer nanofluidic devices have great potential to replace silicon (Si) and glass-based nanofluidic devices in biomedical applications due to their advantages such as low material and fabrication cost, various physicochemical properties, well-developed surface modification protocol, and low electrical noises for electrical measurements. In nanofluidic sensing applications, single molecules such as DNA are introduced into the fabricated nanochannel or nanopore, measuring their physicochemical properties optically or electrically. The properties of materials for nanofluidic devices have a significant role in the performance of the devices, such as DNA translocation and device stability.

Among several nanoscale fluidic physics, surface charge density is a …

A Low-Cost Experimental Testbed For Multi-Agent System Coordination Control, Victor Fernandez-Kim

LSU Master's Theses

A multi-agent system can be defined as a coordinated network of mobile, physical agents that execute complex tasks beyond their individual capabilities. Observations of biological multi-agent systems in nature reveal that these ``super-organisms” accomplish large scale tasks by leveraging the inherent advantages of a coordinated group. With this in mind, such systems have the potential to positively impact a wide variety of engineering applications (e.g. surveillance, self-driving cars, and mobile sensor networks). The current state of research in the area of multi-agent systems is quickly evolving from the theoretical development of coordination control algorithms and their computer simulations to experimental …

Hyperspectral Imaging For Characterizing Single Plasmonic Nanostructure And Single-Cell Analysis, Nishir Sanatkumar Mehta

LSU Master's Theses

Orientation of plasmonic nanostructures is an important feature in many nanoscale applications such as photovoltaics, catalyst, biosensors DNA interactions, protein detections, hotspot of surface-enhanced Raman spectroscopy (SERS), and fluorescence resonant energy transfer (FRET) experiments. Silver nanocubes with significant spectral signatures between 400-700 nm are observed in this experimental research. Whereas study of single cells will enable the analysis of cell-to-cell variations within a heterogeneous population. These variations are important for further analysis and understanding of disease propagation, drug development, stem cell differentiation, embryos development, and how cells respond to each other and their environment. Adipose-derived mesenchymal stem cells possess the …