Mechanical Engineering Commons^™

Direct Simulations Of Cells Motions And Deformations In Flow, Quan Jin

Dissertations

Direct numerical simulations (DNS) are used to study the motions and deformations of blood cells, especially leukocytes, in pressure driven flows in parallel plate channels with both smooth and uneven walls under adhesion force between the leukocytes and the channel wall.

Leukocytes are represented by two composite fluid models. The first model is the compound-drop model in which the cytoplasm and the nucleus are modeled as fluids, and the second one is the drop-rigid-particle model in which the cytoplasm is modeled as a fluid and the nucleus as a rigid particle. The adhesion force is computed using two adhesion force …