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- Animals (1)
- Biocompatible Materials (1)
- Biomaterial (1)
- Biomechanics (1)
- Bone remodeling (1)
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- Cardiac Volume (1)
- Computer Simulation (1)
- Elastic Modulus (1)
- Exercise (1)
- Finite Element Analysis (1)
- Finite Element Modeling (1)
- Finite element anaylsis (1)
- Heart Ventricles (1)
- Hip fracture (1)
- Hydrogels (1)
- Injections (1)
- Left Ventricular Remodeling (1)
- Materials Testing (1)
- Models, Cardiovascular (1)
- Myocardial Infarction (1)
- Proximal femur (1)
- Publication Type
Articles 1 - 2 of 2
Full-Text Articles in Mechanical Engineering
Computational Sensitivity Investigation Of Hydrogel Injection Characteristics For Myocardial Support, Hua Wang, Christopher B. Rodell, Madonna E. Lee, Neville N. Dusaj, Joseph H. Gorman Iii, Jason A. Burdick, Robert C. Gorman, Jonathan F. Wenk
Computational Sensitivity Investigation Of Hydrogel Injection Characteristics For Myocardial Support, Hua Wang, Christopher B. Rodell, Madonna E. Lee, Neville N. Dusaj, Joseph H. Gorman Iii, Jason A. Burdick, Robert C. Gorman, Jonathan F. Wenk
Mechanical Engineering Faculty Publications
Biomaterial injection is a potential new therapy for augmenting ventricular mechanics after myocardial infarction (MI). Recent in vivo studies have demonstrated that hydrogel injections can mitigate the adverse remodeling due to MI. More importantly, the material properties of these injections influence the efficacy of the therapy. The goal of the current study is to explore the interrelated effects of injection stiffness and injection volume on diastolic ventricular wall stress and thickness. To achieve this, finite element models were constructed with different hydrogel injection volumes (150 µL and 300 µL), where the modulus was assessed over a range of 0.1 kPa …
Biomechanical Testing Of An Exercise For Strengthening The Proximal Femur., Alyssa Osbourne
Biomechanical Testing Of An Exercise For Strengthening The Proximal Femur., Alyssa Osbourne
Electronic Theses and Dissertations
Based on the principles of cutting edge bone remodeling research, a unique therapeutic exercise device was designed specifically to improve bone quality at the most critical location of the proximal femur prone to fracture: the superior-lateral femoral neck where the fracture first initiates during a fall. The exercise/device is intended to work by inducing enough strain in the bone to stimulate the body’s natural bone remodeling mechanisms to increase bone density in the proximal femur and consequently prevent a fracture from arising if a fall to the side does occur.
In order to test the proposed exercise, experiments simulating the …