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Biomedical Engineering and Bioengineering
The Summer Undergraduate Research Fellowship (SURF) Symposium
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Articles 1 - 5 of 5
Full-Text Articles in Mechanical Engineering
Development Of Portable Hyperspectral Imaging Device, Chenxi Li, Youngkee Jung, Iyll-Joon Doh, Euiwon Bae
Development Of Portable Hyperspectral Imaging Device, Chenxi Li, Youngkee Jung, Iyll-Joon Doh, Euiwon Bae
The Summer Undergraduate Research Fellowship (SURF) Symposium
Most of the conventional hyperspectral imaging devices require sophisticated optical components, occupy a large footprint, and requires an initial capital investment for laboratories which mostly suits for laboratories benchtop system. The requirement of shipping the sample and waiting an extended period of time to get the results are the main downsides of this traditional approach. Capitalize in many specific field applications and diagnosis, portable devices provide both convenience and on-site results which are desirable for government agencies and food safety inspectors. This project was aimed to develop a low-cost, portable hyperspectral device for food safety applications. A smartphone was used …
Bacterial Motility And Its Role In Biofilm Formation, Clayton J. Culp, Arezoo M. Ardekani, Adib Ahmadzadegan
Bacterial Motility And Its Role In Biofilm Formation, Clayton J. Culp, Arezoo M. Ardekani, Adib Ahmadzadegan
The Summer Undergraduate Research Fellowship (SURF) Symposium
Bacterial biofilms are known to cause millions of dollars in damage in the medical industry per year via infection of central venous catheters, urinary catheters, and mechanical heart valves. Unfortunately, there are some characteristics of biofilm formation that are yet to be fully understood. Recently much work has been done to investigate the motility characteristics of bacteria with hopes of better understanding the phenomena of biofilm formation. Still, one of the least understood stages is bacterial attachment or adhesion, a process designed to anchor bacteria in an advantageous environment. Providing a better understanding of bacterial motility near solid interfaces will …
Intrinsic Regulators Of Actomyosin Contractility Engendering Pulsatile Behaviors, Qilin Yu, Jing Li, Taeyoon Kim
Intrinsic Regulators Of Actomyosin Contractility Engendering Pulsatile Behaviors, Qilin Yu, Jing Li, Taeyoon Kim
The Summer Undergraduate Research Fellowship (SURF) Symposium
Actomyosin contractility regulates various biological processes including cell migration, muscle contraction, and tissue morphogenesis. Cell cortex underlying a membrane, which is a representative actomyosin network in eukaryote cells, exhibits dynamic contractile behaviors. Interestingly, the cell cortex shows reversible aggregation of actin and myosin called pulsatile contraction in diverse cellular phenomena, such as embryogenesis and tissue morphogenesis. While contractile behaviors have been studied in several in vitro experiments and computational studies, none of them demonstrated the pulsatile contraction of actomyosin networks observed in vivo. Here, we used an agent-based computational model based on Brownian dynamics to identify factors facilitating the pulsatile …
Smartphone-Based Microscope For Pathogen Detection, Meghan E. Henderson, Katherine N. Clayton, Ryan M. Preston, Jacqueline Linnes, Tamara L. Kinzer-Ursem
Smartphone-Based Microscope For Pathogen Detection, Meghan E. Henderson, Katherine N. Clayton, Ryan M. Preston, Jacqueline Linnes, Tamara L. Kinzer-Ursem
The Summer Undergraduate Research Fellowship (SURF) Symposium
Vibrio cholerae is a water and food borne bacteria that causes cholera, a severe acute diarrheal disease, when ingested and when left untreated, can cause patient death within hours. Currently there is a lack of both sensitive and rapid portable detection technologies of V. cholerae for testing water and food samples. Combining nucleic acid amplification and particle diffusometry present an alternative detection method for V. cholerae in under 30 minutes, but the process requires an expensive laboratory microscope. In this work, we develop a smartphone-based microscope to detect V. cholerae DNA in environmental water samples using particle diffusometry. A modular …
A Parametric Study Of The Mechanics Of Different Skin Flap Techniques, Steven J. Meza, Adrián Tepole Buganza
A Parametric Study Of The Mechanics Of Different Skin Flap Techniques, Steven J. Meza, Adrián Tepole Buganza
The Summer Undergraduate Research Fellowship (SURF) Symposium
In modern day plastic and reconstructive surgeries numerous skin flap designs have been developed and are used to close open wounds. Skin flaps are developed with the intention of imposing minimal tension in skin closure. Excessive tension can lead to poor blood flow that result in post-surgery complications such as necrosis. Currently there is no standard in choosing a skin flap design and a surgeon's choice is based personal experience. A comparison of the mechanical loading in these various designs has not yet been done. We have developed a parametric study, using finite element analysis, of two advancement skin flaps …