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Full-Text Articles in Mechanical Engineering

Automated Measurement Of Fracture Callus In Radiographs Using Portable Software, Stephen M. Porter, Hannah L. Dailey, Katharine A. Hollar, Karina Klein, James A. Harty, Trevor J. Lujan Jul 2016

Automated Measurement Of Fracture Callus In Radiographs Using Portable Software, Stephen M. Porter, Hannah L. Dailey, Katharine A. Hollar, Karina Klein, James A. Harty, Trevor J. Lujan

Mechanical and Biomedical Engineering Faculty Publications and Presentations

The development of software applications that assist the radiographic evaluation of fracture healing could advance clinical diagnosis and expedite the identification of effective treatment strategies. A radiographic feature regularly used as an outcome measure for basic and clinical fracture healing research is new bone growth, or fracture callus. In this study, we developed OrthoRead, a portable software application that uses image-processing algorithms to detect and measure fracture callus in plain radiographs. OrthoRead utilizes an optimal boundary tracking algorithm to semi-automatically segment the cortical surface, and a novel iterative thresholding selection algorithm to then automatically segment the fracture callus. The software …


Adaptive Kernel Estimation For Enhanced Filtering And Pattern Classification Of Magnetic Resonance Imaging: Novel Techniques For Evaluating The Biomechanics And Pathologic Conditions Of The Lumbar Spine, Nicholas Vincent Battaglia May 2016

Adaptive Kernel Estimation For Enhanced Filtering And Pattern Classification Of Magnetic Resonance Imaging: Novel Techniques For Evaluating The Biomechanics And Pathologic Conditions Of The Lumbar Spine, Nicholas Vincent Battaglia

Doctoral Dissertations

This dissertation investigates the contribution the lumbar spine musculature has on etiological and pathogenic characteristics of low back pain and lumbar spondylosis. This endeavor necessarily required a two-step process: 1) design of an accurate post-processing method for extracting relevant information via magnetic resonance images and 2) determine pathological trends by elucidating high-dimensional datasets through multivariate pattern classification. The lumbar musculature was initially evaluated by post-processing and segmentation of magnetic resonance (MR) images of the lumbar spine, which characteristically suffer from nonlinear corruption of the signal intensity. This so called intensity inhomogeneity degrades the efficacy of traditional intensity-based segmentation algorithms. Proposed …