Mechanical Engineering Commons^™

Finite Element Analysis Of 3d-Printed Pcl Scaffolds, Ireolu K. Orenuga, Joao Soares, Phillip D. Glass, Daeha Joung Ph.D.

Undergraduate Research Posters

Finite Element Analysis of 3D-printed PCL Scaffolds for Synergizing Cellular Micro-Environment and Mechanical Stimuli to Enhance Engineered Tissue Growth in Vitro

Ireolu Orenuga,1 Phillip Glass,2 Daeha Joung,2 Joao S. Soares1

1. Department of Mechanical and Nuclear Engineering, College of Engineering, Virginia Commonwealth University
2. Department of Physics, College of Humanities & Sciences, Virginia Commonwealth University

Introduction: Tissue engineering aims to create viable and functional engineered tissues via biodegradable scaffolds and autologous cells. Scaffolds play an essential part in organizing the architecture of developing tissues and aid in the proper function of implants acutely by serving as mechanical support and long-term by …

The Influence Of Flow Mechanotransduction On Endothelial Cells In The Lymphatic Valve Sinus, Joshua Daniel Hall

Doctoral Dissertations

Fluid flow in the cardiovascular and lymphatic systems influences the phenotype of endothelial cells that line the interior to the vessel via mechanotransduction. Geometric features in a vessel such as curvature, bifurcation, and valves promote heterogeneous fluid flow profiles, inducing a heterogeneous endothelial phenotype within a vessel region. Certain flow conditions are associated with vascular dysfunction, and diseases such as atherosclerosis preferentially develop in areas of flow disturbance. Lymphatic vessels are highly analogous to blood vessels, although lymphatic flow characteristics and its effect on lymphatic endothelial cells (LECs) via mechanotransduction have been comparatively less examined. The most significant geometric features …

A Survey Of Stainless Steel In Medical And Surgical Application, Noah Slack, Clint Balch

ME 4133/6133 Mechanical Metallurgy

Stainless steels can be separated into four families based on the microstructure of the material: Austenitic, Ferritic, Martensitic, and Duplex. Each family provides a specific set of advantages and disadvantages, and material selection should be based on the specific application the material will be used for. For this study, the processing, microstructure, and performance of the four families of stainless steels will be compared in the context of medical device applications. The most important factors in medical device materials are biocompatibility, surface properties, mechanical properties and life span/corrosion resistance. This study will focus on medical devices that will be permanently …

In The Pursuit Of Assistance: A Team's Desire To Not Let A Congenital Amputation Get In A Young Boy's Way, Carl Russell Iii, Gavin Loucks, Kirsten Wozniak

Purdue Journal of Service-Learning and International Engagement

EPICS is a service-learning design program run through Purdue University. It strives to teach students design skills through providing for individuals, communities, and organizations in the surrounding area while mirroring engineering industry standards. BME (Biomedical Engineering) is a team within EPICS that strives to serve community partners through biomedical applications. William Sevick is an elementary school student with a congenital arm amputation. William and his family have been working with the BME team for the past three years designing assistive devices with the purpose of improving his actions in daily life such as eating, playing games, and riding his bike.

Pediatric Blood Calculator, Richard Desatnik

Williams Honors College, Honors Research Projects

This paper outlines an expert system based solution for calculating the optimal amount of blood draw from infants to carry out critical tests requested by the attending clinicians. The solution is a hand-held device with a user-friendly interface that allows a meaningful two-way conversation between the clinician and the pathology office. Based on the tests being requested, the calculator determines the minimum amount of blood required in the different vials based on a smart expert system. This removes the uncertainty that is prevalent today in the amount of blood required to do all the tests, since in some cases there …

The Tera Multi Terrain Mobility Aid Chassis, Colton Kemp, Daniel Nicoll, Ibrahim Suleiman, Mohammad Alyami

Williams Honors College, Honors Research Projects

The natural environment poses a significant number of obstacles and dynamic settings that makes mobility difficult for those with physical and mobility impairments. To approach this problem, a suspension was designed using inspiration from the early Mars rovers developed by NASA for traversing the varied Martian landscape. The course of the project followed the direction of a start-up through problem identification, early design generation and review, and final design production. The project outcome, through client request and proven market research, aimed to produce a multi-terrain wheelchair. The final product is a kinematic body with mobile front “legs” and a rotational …

Design And Evaluation Of Pediatric Gait Rehabilitation Robots, Cale J. Stolle

Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research

Gait therapy methodologies were studied and analyzed for their potential for pediatric patients. Using data from heel, metatarsal, and toe trajectories, a nominal gait trajectory was determined using Fourier transforms for each foot point. These average trajectories were used as a basis of evaluating each gait therapy mechanism. An existing gait therapy device (called ICARE) previously designed by researchers, including engineers at the University of Nebraska-Lincoln, was redesigned to accommodate pediatric patients. Unlike many existing designs, the pediatric ICARE did not over- or under-constrain the patient’s leg, allowing for repeated, comfortable, easily-adjusted gait motions. This design was assessed under clinical …