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Poroelastic Finite Element Analysis Of A Heterogeneous Articular Cartilage Explant Under Dynamic Compression In Abaqus, Kelsey Kiyo Kam
Poroelastic Finite Element Analysis Of A Heterogeneous Articular Cartilage Explant Under Dynamic Compression In Abaqus, Kelsey Kiyo Kam
Master's Theses
A poroelastic finite element model of a heterogeneous articular cartilage disc was
created to examine the tissue response to low amplitude (± 2% strain), low
frequency (0.1 Hz) dynamic unconfined compression (UCC). A strong correlation
has been made between the relative fluid velocity and stimulation of
glycosaminoglycan synthesis. A contour plot of the model shows the relative fluid
velocity during compression exceeds a trigger value of 0.25 μm/s at the radial
periphery. Dynamic UCC biochemical results have also reported a higher
glycosaminoglycan content in this region versus that of day 0 specimens. Fluid
velocity was also found not to be …