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Full-Text Articles in Mechanical Engineering
3d Printed Bioreactor With Optimized Stimulations For Ex-Vivo Bone Tissue Culture, Anirban Chakraborty
3d Printed Bioreactor With Optimized Stimulations For Ex-Vivo Bone Tissue Culture, Anirban Chakraborty
Electronic Theses and Dissertations
Motivation: Long term tissue survivability ex-vivo can greatly facilitate research on the influence of external stimulus (loading, radiation, microgravity) on the tissue, including mechanisms of disease transmission and subsequent drug discoveries. Bioreactors (used to culture living tissue ex-vivo) can be a valuable tool to study cell activity during physiological processes by mimicking their in-vivo native 3D environment.
Objective Statement: We have developed a compact, 3D printed bioreactor equipped with both continuous flow-perfusion and dynamic mechanical-loading stimulations, capable of maintaining ex-vivo viability of swine cancellous bone cores over a long period. Qualitative study of the cultured cores (in terms of …
Lcd 3d Printing Of A Photocurable Elastomer For Tissue Engineering, Beatriz Luiza De Souza
Lcd 3d Printing Of A Photocurable Elastomer For Tissue Engineering, Beatriz Luiza De Souza
Electronic Theses and Dissertations
Three-dimensional scaffolding is an emerging research area in biomedical and tissue engineering. Scaffolds provide the possibility of growing tissues in a controlled environment, with desired characteristics and properties towards a specific application. A new method to 3D print biodegradable and biocompatible material called Polyglycerol Sebacate Acrylate (PGSA) is demonstrated. PGSA is essentially an acrylated form of PGS using photoinitiator to become a photocurable resin suitable for liquid crystal display (LCD) 3D printing. PGSA was selected because its rheological and crosslinking behavior (and hence its mechanical properties) can be controlled by changes in curing time, temperature, and pressure. This material has …
Bio Inspired Lightweight Composite Material Design For 3d Printing, Kaushik Thiyagarajan
Bio Inspired Lightweight Composite Material Design For 3d Printing, Kaushik Thiyagarajan
Electronic Theses and Dissertations
Lightweight material design is an indispensable subject in product design. The lightweight material design has high strength to weight ratio which becomes a huge attraction and an area of exploration for the researchers as its application is wide and increasing even in every day-to-day product. Lightweight composite material design is achieved by selection of the cellular structure and its optimization. Cellular structure is used as it has wide multifunctional properties in addition to the lightweight characteristics. Applications of light weight cellular structures are wide and is witnessed in all industries from aerospace to automotive, construction to product design. In this …