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Full-Text Articles in Mechanical Engineering

Simvastatin Improves Spinal Fusion In Rats, Bora Bostan, Taner Güneş, Murat Aşçi, Cengiz Şen, Mehmet Halidun Keleştemur, Mehmet Erdem, Reşit Doǧan Köseoǧlu, Ünal Erkorkmaz Dec 2011

Simvastatin Improves Spinal Fusion In Rats, Bora Bostan, Taner Güneş, Murat Aşçi, Cengiz Şen, Mehmet Halidun Keleştemur, Mehmet Erdem, Reşit Doǧan Köseoǧlu, Ünal Erkorkmaz

Faculty Publications - Mechanical Engineering

Objective: Statins stimulate bone formation by inducing the expression of bone morphogenetic proteins (BMP-2). The aim of our study was to investigate the effects of orally administered simvastatin on spinal fusion in rats. Methods: Twenty rats were randomized into a spinal fusion group (SF) (n=10) or a spinal fusion and oral simvastatin administered group (SFS) (n=10). A spinal fusion was performed between L4-L6 representing two levels. Simvastatin (120 mg/kg/day) was administered orally in the SFS group. The rats were killed at the end of the 12 week study period. Results: Manual palpation revealed two moderate fusions in the SF group. …


A Biomechanical Comparison Of Polymethylmethacrylate-Reinforced And Expansive Pedicle Screws In Pedicle-Screw Revisions, Bora Bostan, Irfan Esenkaya, Taner Gunes, Mehmet Erdem, Murat Asci, Mehmet Halidun Kelestemur, Cengiz Sen Dec 2009

A Biomechanical Comparison Of Polymethylmethacrylate-Reinforced And Expansive Pedicle Screws In Pedicle-Screw Revisions, Bora Bostan, Irfan Esenkaya, Taner Gunes, Mehmet Erdem, Murat Asci, Mehmet Halidun Kelestemur, Cengiz Sen

Faculty Publications - Mechanical Engineering

Objectives: Different techniques and choices exist for revision of pedicle screws, two of which are pedicle screw combined with cement augmentation and expansive pedicle screw fixation. This biomechanical study was designed to compare the pullout strengths of two different revision techniques. Methods: Fourteen lumbar vertebrae obtained from four calves (mean age 15 months) were divided into two groups equal in number. Monoaxial 6.0-mm pedicle screws were inserted into the right pedicles, and axial pullout testing was performed at a rate of 10 mm/min and failure strengths were recorded. Revision was performed with the same-sized pedicle screws reinforced with polymethyl-methacrylate in …


Comparison Of The Pull-Out Strengths Of Three Different Screws In Pedicular Screw Revisions: A Biomechanical Study, Irfan Esenkaya, Yurdaer Denizhan, Mehmet Akif Kaygusuz, Mehmet Yetmez, Mehmet Halidun Keleştemur Jan 2006

Comparison Of The Pull-Out Strengths Of Three Different Screws In Pedicular Screw Revisions: A Biomechanical Study, Irfan Esenkaya, Yurdaer Denizhan, Mehmet Akif Kaygusuz, Mehmet Yetmez, Mehmet Halidun Keleştemur

Faculty Publications - Mechanical Engineering

OBJECTIVES: We investigated the possible effects of three pedicular screws on axial pull-out strength in pedicular revision surgery. METHODS: Two study groups were formed from calf lumbar vertebrae. Initially, Alici pedicular screws with an outer diameter of 6.5 mm were applied (with or without tapping) to all the pedicles. All the pedicles were subjected to axial pull-out testing to induce pedicular insufficiency. Then, Alici pedicular screws with an outer diameter of 7 mm were applied to the left pedicles. The right pedicles in the two study groups were assigned to receive two different types of pedicular screws with an expandable …