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Full-Text Articles in Mechanical Engineering
A Method To Develop Neck Injury Criteria To Aid Design And Test Of Escape Systems Incorporating Helmet Mounted Displays, Jeffrey C. Parr
A Method To Develop Neck Injury Criteria To Aid Design And Test Of Escape Systems Incorporating Helmet Mounted Displays, Jeffrey C. Parr
Theses and Dissertations
HMDs are becoming common human-machine interface equipment in manned military flight, but introducing this equipment into the overall aircraft escape system poses new and significant system design, development, and test concerns. Although HMDs add capabilities, which improve operator performance, the increased capability is often accompanied by increased head supported mass. The increased mass can amplify the risk of pilot neck injury during ejection when compared to lighter legacy helmets. Currently no adequate USAF neck injury criteria exist to effectively guide the requirements, design, and test of escape systems for pilots with HMDs. This research effort presents a novel method to …
Cfd Assessment Of Respiratory Drug Delivery Efficiency In Adults And Improvements Using Controlled Condensational Growth, Ross L. Walenga
Cfd Assessment Of Respiratory Drug Delivery Efficiency In Adults And Improvements Using Controlled Condensational Growth, Ross L. Walenga
Theses and Dissertations
Pharmaceutical aerosols provide a number of advantages for treating respiratory diseases that include targeting high doses directly to the lungs and reducing exposure of other organs to the medication, which improve effectiveness and minimize side effects. However, difficulties associated with aerosolized drug delivery to the lungs include drug losses in delivery devices and in the extrathoracic region of human upper airways. Intersubject variability of extrathoracic and thoracic drug deposition is a key issue as well and should be minimized. Improvements to respiratory drug delivery efficiency have been recently proposed by Dr. P. Worth Longest and Dr. Michael Hindle through the …
Modeling Acute Changes In Bladder Wall Tension, Shape And Compliance During Filling, Firdaweke Habteyes
Modeling Acute Changes In Bladder Wall Tension, Shape And Compliance During Filling, Firdaweke Habteyes
Theses and Dissertations
The bladder wall consists primarily of detrusor smooth muscle. Tension-sensitive nerves in the bladder wall are responsible for providing bladder fullness information that is interpreted as urgency. Bladder wall tension, and therefore nerve output, is a function of bladder volume, shape and material properties. Studies have shown that the bladder wall exhibits acutely regulated detrusor compliance. In addition, bladder shape throughout filling depends on intra-abdominal forces and material properties of the bladder wall, such as regulated detrusor compliance. This thesis focused on modeling the potential influence of acute changes in bladder compliance, shape and bladder wall tension during filling. Laplace’s …
Analysis And Modeling Of The Roles Of Actin-Myosin Interactions In Bladder Smooth Muscle Biomechanics, Seyed Omid Komariza
Analysis And Modeling Of The Roles Of Actin-Myosin Interactions In Bladder Smooth Muscle Biomechanics, Seyed Omid Komariza
Theses and Dissertations
Muscle mechanical behavior potentially plays an important role in some of the most common bladder disorders. These include overactive bladder, which can involve involuntary contractions during bladder filling, and impaired contractility or underactive bladder, which may involve weak or incomplete contractions during voiding. Actin-myosin cross-bridges in detrusor smooth muscle (DSM) are responsible for contracting and emptying the bladder. The total tension produced by muscle is the sum of its preload and active tensions. Studies suggest that actin-myosin cross-links are involved in adjustable preload stiffness (APS), which is characterized by a preload tension curve that can be shifted along the length …