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Full-Text Articles in Mechanical Engineering
Development Of A Shape Memory Polymer Soft Microgripper, Marshall Tatro, David J. Cappelleri, Wuming Jing
Development Of A Shape Memory Polymer Soft Microgripper, Marshall Tatro, David J. Cappelleri, Wuming Jing
The Summer Undergraduate Research Fellowship (SURF) Symposium
The ability to control microrobots by means of magnetic fields has become of increasing interest to researchers. These robots’ ability to reach places tethered microrobots otherwise could not leads to many possible applications in the body, such as delivering drugs to targeted locations and performing biopsies. This study shows the use of shape memory polymer (SMP) to wirelessly actuate a microgripper to be used by a controllable microrobot to achieve these functions. Many smart materials were analyzed in order to find the material that most effectively would accomplish wirelessly gripping, manipulating, and releasing a microobject. Multiple microgripper designs were designed, …
Indentation Probing Of In Vitro Bovine Articular Cartilage: Effects On Chondrocyte Viability And Tissue Biomechanics, Pablo F. Argote, Alan Poon, Xin Xu Ph.D, Corey P. Neu Ph.D.
Indentation Probing Of In Vitro Bovine Articular Cartilage: Effects On Chondrocyte Viability And Tissue Biomechanics, Pablo F. Argote, Alan Poon, Xin Xu Ph.D, Corey P. Neu Ph.D.
The Summer Undergraduate Research Fellowship (SURF) Symposium
Osteoarthritis (OA) consists of a degenerative disease on articular cartilage, which is prone to excessive mechanical loading and frictional resistance that leads to the wear and tear of the tissue. These factors result in the progressive and incurable disease that affects millions of people worldwide. The goal is to characterize chondrocyte viability and the in vitro biomechanical properties of articular cartilage in two confined indentation studies. One study looks at the chondrocyte viability over seven days. The second compares the immediate effects of strain rates on chondrocyte viability and tissue biomechanics. Bovine cartilage explants are harvested, cultured, and then 40% …
Cell-Matrix Interactions During En Masse Cell Migration, Meng Zhuang, Altug Ozcelikkale, Bumsoo Han
Cell-Matrix Interactions During En Masse Cell Migration, Meng Zhuang, Altug Ozcelikkale, Bumsoo Han
The Summer Undergraduate Research Fellowship (SURF) Symposium
Extended wound care, including prolonged treatment of burn injuries, acute and chronic wounds, is a significant source of patient discomfort and financial burden to public healthcare programs. Both accelerated healing and prevention of scar formation are highly desired but remain to be challenging to achieve. This is primary due to limited understanding of interactions between cells and the surrounding extracellular matrix (ECM) during wound healing. Particularly, collective migration of fibroblasts through provisional matrix, so called en masse migration, is one of these interactions that play a critical role in later stages of granulation tissue formation and wound closure. In addition …