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Full-Text Articles in Mechanical Engineering
Evaluation Of Novel High-Density Emg Feedback Parameters On The Spatial Distribution Of Trapezius Muscle Activity, Brecca M. Gaffney
Evaluation Of Novel High-Density Emg Feedback Parameters On The Spatial Distribution Of Trapezius Muscle Activity, Brecca M. Gaffney
Electronic Theses and Dissertations
Each year, 17.9% of adults working in a computer-dominated work environment develop an episode of chronic neck and shoulder pain. An effective treatment method for chronic pain is postural correction through therapist. The understanding of the relation between cervicoscapular posture and trapezius muscle activity is not fully understood because the anatomy of the scapula is not accessible for direct observation. Until recently, the spatial distribution of trapezius muscle activity could not be measured due to the limitation in size of detection zone in traditional bipolar electrodes. The primary goal of postural correction when treating cases of chronic neck and shoulder …
Cavitation In Pharmaceutical Manufacturing And Shipping, Donn Sederstrom
Cavitation In Pharmaceutical Manufacturing And Shipping, Donn Sederstrom
Electronic Theses and Dissertations
Therapeutic proteins are used to successfully treat hemophilia, Crohn's Disease, diabetes, and cancer. Recent product recalls have occurred because of sub-visible particle formation resulting from the inherent instability of proteins. It has been suggested that particle formation is associated with late stage processing steps of filling, shipping, and delivery. Previous work at the University of Denver demonstrated that fluid cavitation can generate a large number of sub-visible protein particles in ultra clean formulations, but that mitigation can be achieved with fluid property manipulation. The goal of this research was to (1) assess the risk of cavitation under common pharmaceutical manufacturing …