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Biomechanical Engineering

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California Polytechnic State University, San Luis Obispo

Osteoarthritis

Publication Year

Articles 1 - 4 of 4

Full-Text Articles in Mechanical Engineering

Subject-Specific Finite Element Predictions Of Knee Cartilage Pressure And Investigation Of Cartilage Material Models, Michael G. Rumery Sep 2018

Subject-Specific Finite Element Predictions Of Knee Cartilage Pressure And Investigation Of Cartilage Material Models, Michael G. Rumery

Master's Theses

An estimated 27 million Americans suffer from osteoarthritis (OA). Symptomatic OA is often treated with total knee replacement, a procedure which is expected to increase in number by 673% from 2005 to 2030, and costs to perform total knee replacement surgeries exceeded $11 billion in 2005. Subject-specific modeling and finite element (FE) predictions are state-of-the-art computational methods for anatomically accurate predictions of joint tissue loads in surgical-planning and rehabilitation. Knee joint FE models have been used to predict in-vivo joint kinematics, loads, stresses and strains, and joint contact area and pressure. Abnormal cartilage contact pressure is considered a risk factor …


Human Knee Fea Model For Transtibial Amputee Tibial Cartilage Pressure In Gait And Cycling, Gregory Lane Jun 2018

Human Knee Fea Model For Transtibial Amputee Tibial Cartilage Pressure In Gait And Cycling, Gregory Lane

Master's Theses

Osteoarthritis (OA) is a debilitating disease affecting roughly 31 million Americans. The incidence of OA is significantly higher for persons who have suffered a transtibial amputation. Abnormal cartilage stress can cause higher OA risk, however it is unknown if there is a connection between exercise type and cartilage stress. To help answer this, a tibiofemoral FEA model was created. Utilizing linear elastic isotropic materials and non-linear springs, the model was validated to experimental cadaveric data. In a previous study, 6 control and 6 amputee subjects underwent gait and cycling experiments. The resultant knee loads were analyzed to find the maximum …


Development And Validation Of A Tibiofemoral Joint Finite Element Model And Subsequent Gait Analysis Of Intact Acl And Acl Deficient Individuals, Nicholas Czapla Jun 2015

Development And Validation Of A Tibiofemoral Joint Finite Element Model And Subsequent Gait Analysis Of Intact Acl And Acl Deficient Individuals, Nicholas Czapla

Master's Theses

Osteoarthritis (OA) is a degenerative condition of articular cartilage that affects more than 25 million people in the US. Joint injuries, like anterior cruciate ligament (ACL) tears, can lead to OA due to a change in articular cartilage loading. Gait analysis combined with knee joint finite element modeling (FEM) has been used to predict the articular cartilage loading. To predict the change of articular cartilage loading during gait due to various ACL injuries, a tibiofemoral FEM was developed from magnetic resonance images (MRIs) of a 33 year male, with no prior history of knee injuries. The FEM was validated for …


Development And Validation Of A Human Knee Joint Finite Element Model For Tissue Stress And Strain Predictions During Exercise, Spencer D. Wangerin Dec 2013

Development And Validation Of A Human Knee Joint Finite Element Model For Tissue Stress And Strain Predictions During Exercise, Spencer D. Wangerin

Master's Theses

Osteoarthritis (OA) is a degenerative condition of cartilage and is the leading cost of disability in the United States. Motion analysis experiments in combination with knee-joint finite element (FE) analysis may be used to identify exercises that maintain knee-joint osteochondral (OC) loading at safe levels for patients at high-risk for knee OA, individuals with modest OC defects, or patients rehabilitating after surgical interventions. Therefore, a detailed total knee-joint FE model was developed by modifying open-source knee-joint geometries in order to predict OC tissue stress and strain during the stance phase of gait. The model was partially validated for predicting the …