Mechanical Engineering Commons^™

Subject-Specific Finite Element Predictions Of Knee Cartilage Pressure And Investigation Of Cartilage Material Models, Michael G. Rumery

Master's Theses

An estimated 27 million Americans suffer from osteoarthritis (OA). Symptomatic OA is often treated with total knee replacement, a procedure which is expected to increase in number by 673% from 2005 to 2030, and costs to perform total knee replacement surgeries exceeded $11 billion in 2005. Subject-specific modeling and finite element (FE) predictions are state-of-the-art computational methods for anatomically accurate predictions of joint tissue loads in surgical-planning and rehabilitation. Knee joint FE models have been used to predict in-vivo joint kinematics, loads, stresses and strains, and joint contact area and pressure. Abnormal cartilage contact pressure is considered a risk factor …

Poroelastic Finite Element Analysis Of A Heterogeneous Articular Cartilage Explant Under Dynamic Compression In Abaqus, Kelsey Kiyo Kam

Master's Theses

A poroelastic finite element model of a heterogeneous articular cartilage disc was

created to examine the tissue response to low amplitude (± 2% strain), low

frequency (0.1 Hz) dynamic unconfined compression (UCC). A strong correlation

has been made between the relative fluid velocity and stimulation of

glycosaminoglycan synthesis. A contour plot of the model shows the relative fluid

velocity during compression exceeds a trigger value of 0.25 μm/s at the radial

periphery. Dynamic UCC biochemical results have also reported a higher

glycosaminoglycan content in this region versus that of day 0 specimens. Fluid

velocity was also found not to be …