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Full-Text Articles in Mechanical Engineering
Medical Applications Of Ultrasound: T-Cell Drug Delivery, Osteoporosis Diagnosis, And Biofilm Mitigation, Alina Karki
Medical Applications Of Ultrasound: T-Cell Drug Delivery, Osteoporosis Diagnosis, And Biofilm Mitigation, Alina Karki
Graduate College Dissertations and Theses
The ability of ultrasound to localize acoustic energy deposition and induce a biological effect within a target is examined in three novel biomedical applications: sonoporation, osteoporosis diagnosis, and biofilm mitigation.Ultrasound can excite encapsulated microbubbles, causing an acoustic cavitation effect in the vicinity of cells, temporarily increasing membrane permeability, and allowing cells to uptake foreign molecules. This non-viral transfection technique is called sonoporation. Our experimental study demonstrated that it could be effective for small interfering RNA (siRNA) delivery into an isolated mouse and human T-cells, which is a complex process despite its importance in treating numerous diseases. T-cells are non-proliferating, while …
3d Acoustic Pipe Locator Imaging Based On Finite Element Analysis, Yi Liu
3d Acoustic Pipe Locator Imaging Based On Finite Element Analysis, Yi Liu
Graduate College Dissertations and Theses
A more complex underground pipe system is growing with the expansion of cities. However, there is no comprehensive database of underground pipes. Thus, it is urgent to build database with materials, positions, diameters, and etc. To locate the pipes is the first step. There are many ways to find pipes such as metal detector, ground penetrating radar, and acoustic method. Metal detectors are becoming increasing ineffective with more and more nonmetal is using in pipes. Ground penetrating radar is a precise way to find pipes but it is only works well under low moisture environment. Additionally, ground penetrating radar is …
Monitor: Automation Tools For Landscape-Scale Acoustic Monitoring, Jonathan Edward Katz
Monitor: Automation Tools For Landscape-Scale Acoustic Monitoring, Jonathan Edward Katz
Graduate College Dissertations and Theses
Climate change coupled with land-use change will likely alter habitats and affect state parameters of the animal populations that dwell in them. Affected parameters are anticipated to include site occupancy and abundance, population range, and phenophase cycles (e.g., arrival dates on breeding grounds for migrant bird species). Detecting these changes will require monitoring many sites for many years, a process that is well suited for an automated system. We developed and tested monitoR, an R package that is designed for long-term, multi-taxa automated passive acoustic monitoring programs. monitoR correctly identified presence for black-throated green warbler and ovenbird in 64% and …
Nonlinear Ball Chain Waveguides For Acoustic Emission And Ultrasound Sensing Of Ablation, Stephen Herbert Pearson
Nonlinear Ball Chain Waveguides For Acoustic Emission And Ultrasound Sensing Of Ablation, Stephen Herbert Pearson
Graduate College Dissertations and Theses
Harsh environment acoustic emission and ultrasonic wave sensing applications often benefit from placing the sensor in a remote and more benign physical location by using waveguides to transmit elastic waves between the structural location under test and the transducer. Waveguides are normally designed to have high fidelity over broad frequency ranges to minimize distortion - often difficult to achieve in practice. This thesis reports on an examination of using nonlinear ball chain waveguides for the transmission of acoustic emission and ultrasonic waves for the monitoring of thermal protection systems undergoing severe heat loading, leading to ablation and similar processes. Experiments …