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Full-Text Articles in Materials Science and Engineering
Detection Of Methylation On Dsdna Using Nanopores In Mos2 Membrane, David Estrada
Detection Of Methylation On Dsdna Using Nanopores In Mos2 Membrane, David Estrada
Materials Science and Engineering Faculty Publications and Presentations
Methylation at the 5-carbon position of the cytosine nucleotide base in DNA has been shown to be a reliable diagnostic biomarker for carcinogenesis. Early detection of methylation and intervention could drastically increase the effectiveness of therapy and reduce the cancer mortality rate. Current methods for detecting methylation involve bisulfite genomic sequencing, which are cumbersome and demand a large sample size of bodily fluids to yield accurate results. Hence, more efficient and cost effective methods are desired. Based on our previous work, we present a novel nanopore-based assay using a nanopore in a MoS2 membrane, and the methyl-binding protein (MBP), …
Phase Separation In Ti-6al-4v Alloys With Boron Additions For Biomedical Applications: Scanning Kelvin Probe Force Microscopy Investigation Of Microgalvanic Couples And Corrosion Initiation, P. H. Davis, K. Robles, K. Livingston, S. Johns, V. A. Ravi, E. Graugnard, M. F. Hurley
Phase Separation In Ti-6al-4v Alloys With Boron Additions For Biomedical Applications: Scanning Kelvin Probe Force Microscopy Investigation Of Microgalvanic Couples And Corrosion Initiation, P. H. Davis, K. Robles, K. Livingston, S. Johns, V. A. Ravi, E. Graugnard, M. F. Hurley
Materials Science and Engineering Faculty Publications and Presentations
To investigate the effect of boron additions on the corrosion behavior of Ti-6Al-4V for potential use in biomedical implants and devices, cast samples of Ti-6Al-4V were alloyed with 0.01% to 1.09% boron by weight and subjected to hot isostatic pressing. Subsequent analysis via scanning Kelvin probe force microscopy and scanning electron microscopy/energy-dispersive spectroscopy revealed the presence of both alpha (α) and beta (β) phase titanium, enriched in aluminum and vanadium, respectively. At all concentrations, boron additions affected the grain structure and were dispersed throughout both phases, but above the solubility limit, needle-like TiB structures also formed. …
Vertically Integrated Projects (Vip) Programs: Multidisciplinary Projects With Homes In Any Discipline, Jocelyn B. S. Cullers, William L. Hughes, Donna C. Llewellyn
Vertically Integrated Projects (Vip) Programs: Multidisciplinary Projects With Homes In Any Discipline, Jocelyn B. S. Cullers, William L. Hughes, Donna C. Llewellyn
Materials Science and Engineering Faculty Publications and Presentations
A survey of papers in the ASEE Multidisciplinary Engineering Division over the last three years shows three main areas of emphasis: individual courses; profiles of specific projects; and capstone design courses. However, propagating multidisciplinary education across the vast majority of disciplines offered at educational institutions with varying missions requires models that are independent of the disciplines, programs, and institutions in which they were originally conceived. Further, models that can propagate must be cost effective, scalable, and engage and benefit participating faculty. Since 2015, a consortium of twenty-four institutions has come together around one such model, the Vertically Integrated Projects (VIP) …