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Full-Text Articles in Materials Science and Engineering
Exploring Rapid Solidification And Equal Channel Angular Pressing In The Fabrication Of Mg-Based Alloys For Medical Applications, Emily Tom
Dissertations, Master's Theses and Master's Reports
The development of magnesium bioresorbable implants has become increasingly popular due to the increased need for temporary implants and magnesium’s excellent biocompatibility and suitable elastic modulus. Even though magnesium is an excellent candidate, when alloyed with other metals magnesium’s corrosion rate becomes too rapid for bioresorbable medical applications. The investigation into novel processing techniques to control the formation of precipitates to improve mechanical strength and ductility as well as corrosion rates has become of interest. This work investigates the combination of two nonequilibrium processing techniques, rapid solidification (RS) and equal channel angular pressing (ECAP), and the effects it has on …
Studying Mass And Mechanical Property Changes During The Degradation Of A Bioadhesive With Mass Tracking, Rheology And Magnetoelastic (Me) Sensors, Zhongtian Zhang
Studying Mass And Mechanical Property Changes During The Degradation Of A Bioadhesive With Mass Tracking, Rheology And Magnetoelastic (Me) Sensors, Zhongtian Zhang
Dissertations, Master's Theses and Master's Reports
In this research, the degradable polymer 4-arm poly (ethylene glycol)-glutaric acid-dopamine (PEG-GA-DM4) was synthesized. The degradation behavior of crosslinked PEG-GA-DM4 bioadhesive was studied with mass tracking, oscillatory rheology, and magnetoelastic (ME) sensors. Changes in mechanical properties were correlated with both dry mass and wet mass changes during the degradation. The results indicate that the loss of mechanical property in the bioadhesive can take place without losing the dry mass. The mass loss profile cannot describe the degradation behavior completely. In addition to studying the degradation of PEG-GA-DM4, this research also confirms the application of ME …
Formulation And Testing Of Biodegradable Polymeric Coating On Zinc Wires In Cardiovascular Stent Application, Avishan Arab Shomali
Formulation And Testing Of Biodegradable Polymeric Coating On Zinc Wires In Cardiovascular Stent Application, Avishan Arab Shomali
Dissertations, Master's Theses and Master's Reports
Biodegradable and biocompatible poly (L-lactic-acid) (PLLA) coating was applied on a modified zinc (Zn) substrate by dip coating, with the intent to delay the bio-corrosion and slow the degradation rate of zinc substrate. 3-(Trimethoxysilyl) propyl methacrylate (MPS) was used for modification of the zinc substrate for promoting the adhesion between the metallic substrate and the polymer coating. It is hypothesized that the delay in Zn biodegradation could be useful in the first several weeks to prevent the early loss of mechanical integrity of the endovascular stent and to improve the healing process of the diseased vascular site. The PLLA coating …
Biocorrosion Rate And Mechanism Of Metallic Magnesium In Model Arterial Environments, Patrick Bowen
Biocorrosion Rate And Mechanism Of Metallic Magnesium In Model Arterial Environments, Patrick Bowen
Dissertations, Master's Theses and Master's Reports
A new paradigm in biomedical engineering calls for biologically active implants that are absorbed by the body over time. One popular application for this concept is in the engineering of endovascular stents that are delivered concurrently with balloon angioplasty. These devices enable the injured vessels to remain patent during healing, but are not needed for more than a few months after the procedure. Early studies of iron- and magnesium-based stents have concluded that magnesium is a potentially suitable base material for such a device; alloys can achieve acceptable mechanical properties and do not seem to harm the artery during degradation. …