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Full-Text Articles in Materials Science and Engineering

Glycan Functionalization Of Iron Oxide Nanoparticles (Ionps) As A Method Of Inactivating Antibiotic Resistant Neisseria Gonorrhoeae Via A Magnetically Mediated Energy Delivery (Magmed) System, Cedric Taylor Dec 2021

Glycan Functionalization Of Iron Oxide Nanoparticles (Ionps) As A Method Of Inactivating Antibiotic Resistant Neisseria Gonorrhoeae Via A Magnetically Mediated Energy Delivery (Magmed) System, Cedric Taylor

All Theses

With the increase of antibiotic resistant bacteria, current established therapeutic treatment methods are rapidly demonstrating decreasing efficacy. For this project, we are studying a novel alternate mechanism of treating antibiotic resistant bacteria by utilizing magnetic iron oxide nanoparticles (IONPs) coated with a heterobifunctional polyethylene glycol polymer (PEG) and functionalized with glycan structures that can interact with Neisseria gonorrhoeae FA1090. Interaction between the IONPs and bacteria is manipulated by an external alternating magnetic field (AMF) in a process known as magnetically mediated energy delivery (MagMED). Magnetic IONPs were synthesized and reacted with PEG (PEG-IONPs) and functionalized with glycans Gal(α1-3)Gal(β1-4)Glc(β1-1) (common name: …


Relationship Between Peel Force, Opening Force, And Burst Force For A Semi-Rigid Cup And Lid, Pre- And Post-Retort, Raj Navalakha Dec 2014

Relationship Between Peel Force, Opening Force, And Burst Force For A Semi-Rigid Cup And Lid, Pre- And Post-Retort, Raj Navalakha

All Theses

This research determines if there is any relationship between the peel force, the opening force and the burst force for a semi-rigid cup and lid system, for pre- and post-retort conditions. It also compares the relationship (regression lines) between these forces pre- and post-retort. These seal results were studied by varying the sealing parameters of dwell time and temperature while keeping the pressure constant. Polypropylene cups and a peelable barrier retort lidding were used in this study. As compared to past research, a different peel testing technique was used to measure the peel and the opening force. The entire lid …