Engineering Science and Materials Commons^™

Synthesis And Evaluation Of Sensitizer Drug Photorelease Chemistry: Micro-Optic Method Applied To Singlet Oxygen Generation And Drug Delivery, Goutam Ghosh

Dissertations, Theses, and Capstone Projects

This thesis summarizes a new micro-optic method for singlet oxygen generation and sensitizer drug delivery, which include i) synthesis and evaluation of a first generation device for drug delivery from native and fluorinated silica probe tips, ii) synthesis of PEG conjugated sensitizers to study phototoxicity in ovarian cancer cells, and iii) synthesis and evaluation of tris-PEGylated chlorin conjugated fluorinated silica for its future integration into the device to use as a 2nd generation device. A first generation micro-optic device was developed that works by sparging O2 gas and light generating cytotoxic singlet oxygen that cleaves the covalently attached drug (sensitizer) …

Synthesis, Fabrication And Characterization Of Magnetic And Dielectric Nanoparticles And Nanocomposite Films, Xiaohua Liu

Dissertations, Theses, and Capstone Projects

Materials science is an interdisciplinary field investigating the structure-property relationship in solid-state materials scientifically and technologically. Nanoscience is concerned with the distinctive properties that matter exhibits when confined to physical dimensions on the order of 10^-9 meters. At these length scales, behaviors of particles or elaborate structures are often governed by the rules of quantum mechanics in addition to the physical properties associated with the bulk material.

The work reported here seeks to employ nanocystals, binary nanocomposites and thin films of materials, to build versatile, functional systems and devices. With a focus on dielectric, ferroelectric, and magnetoelectric performance, a …

Characterization Of Wide Band Gap Semiconductors And Multiferroic Materials, Bo Cai

Dissertations, Theses, and Capstone Projects

Structural, optical and electrical properties of zinc oxide (ZnO), aluminum nitride (AlN), and lutetium ferrite (LuFe₂O4) have been investigated. Temperature dependent Hall Effect measurements were performed between 80 and 800 K for phosphorus (P) and arsenic (As) doped ZnO thin films grown on c-plane sapphire substrate by RF magnetron sputtering. These samples exhibited n-type conductivity throughout the temperature range with carrier concentration of 3.85 × 10 ¹⁶ cm^-3 and 3.65 × 10 ¹⁷ cm^-3 at room temperature for P-doped and As-doped ZnO films, respectively. The Arrhenius plots of free electron concentration of those doped samples showed …

Metal Nanoparticles Immobilized On Basic Supports As Catalysts For Hydrogenation And Dehydrogenation Reactions Of Relevance To Cleaner Fossil Fuels And Alternative Sources Of Energy, Reena Rahi

Dissertations, Theses, and Capstone Projects

We developed a series of catalysts, composed of metal nanoparticles immobilized on basic supports for the hydrogenation of heteroaromatics of relevance to cleaner fossil fuels and biodiesel, and for the dehydrogenation of heteroaromatics of relevance to hydrogen storage in organic liquids. Our catalyst design involves nanostructured catalysts composed of metal particles immobilized on basic supports capable of ionic mechanism that may avoid catalyst poisoning and enhance catalytic activity.

We prepared a new catalyst composed of Pd nanoparticles immobilized on MgO by NaBH4 reduction of Na2PdCl4 in methanol in the presence of the support. TEM measurements revealed well-dispersed 1.7 nm Pd …

Organic Pi-Stacking Semiconducting Material: Design, Synthesis And The Analysis Of Structure And Properties, Bin Wang

Dissertations, Theses, and Capstone Projects

Organic semiconducting materials have been under intensive investigation in the recent decades for potential applications in various electronic or optoelectronic devices such as light emitting diodes, photovoltaic cells and field effect transistors. Compared to inorganic counterparts, organic charge transport materials are attractive for their abilities of forming thin-films, large area manufacturing, compatibility with flexible substrate, light weight and potential low fabrication cost. The charge transport property of the organic active layer is one of the key factors to the electronic or optoelectronic performance of devices. Research projects presented in this thesis focused on improving charge carrier mobility of organic charge …