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Engineering Science and Materials Commons

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Biomedical

PCL

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Full-Text Articles in Engineering Science and Materials

On Demand 3d Printed Hybrid Scaffolds For Tissue Engineering Applications, Ivan D. Hernandez Jan 2017

On Demand 3d Printed Hybrid Scaffolds For Tissue Engineering Applications, Ivan D. Hernandez

Open Access Theses & Dissertations

A composite 3D printed polymer scaffold with inbuilt porosity and filled with a hydrogel can provide an ideal support system for cell growth, proliferation, and vascularization. Therefore, a hybrid system of 3D printed polycaprolactone (PCL) scaffold and a hydroxyapatite-based hydrogel was developed for application in the reconstruction of bone defects, which are inherently difficult to repair without any guided therapies. In the present study, a 3D printed gyroid structure of PCL allowed the loading of a higher amount of hydrogel as compared to conventionally used 3D printed mesh structure of the same volume and strut thickness. The hydrogel was composed …


Raman And Infrared Study Of Electrospun Plla/Pcl Nanofiber Blends For Use In Tissue Engineering, Jose Luis Enriquez Carrejo Jan 2012

Raman And Infrared Study Of Electrospun Plla/Pcl Nanofiber Blends For Use In Tissue Engineering, Jose Luis Enriquez Carrejo

Open Access Theses & Dissertations

Recently, the biomedical engineering field has developed at a very fast pace as improved techniques and materials become available to promote its growth. Consequently, the research in polymeric biomaterials has been highly stimulated by this trend. The goal of the current research is to demonstrate the usefulness of the Raman scattering, Raman mapping, and infrared absorption spectroscopies to tissue engineering, by spectroscopically characterizing blends of PLLA and PCL polymers, which were prepared by electrospinning with and without cell addition. The proposed use of these blends is as primary biomaterials in biodegradable scaffolds used in tissue engineering. Both Raman and infrared …