Electrical and Computer Engineering Commons^™

A Machine Learning Framework For Identifying Molecular Biomarkers From Transcriptomic Cancer Data, Md Abdullah Al Mamun

FIU Electronic Theses and Dissertations

Cancer is a complex molecular process due to abnormal changes in the genome, such as mutation and copy number variation, and epigenetic aberrations such as dysregulations of long non-coding RNA (lncRNA). These abnormal changes are reflected in transcriptome by turning oncogenes on and tumor suppressor genes off, which are considered cancer biomarkers.

However, transcriptomic data is high dimensional, and finding the best subset of genes (features) related to causing cancer is computationally challenging and expensive. Thus, developing a feature selection framework to discover molecular biomarkers for cancer is critical.

Traditional approaches for biomarker discovery calculate the fold change for each …

Artificial Intelligent Based Energy And Demand Side Management For Microgrids And Smart Homes Considering Customer Privacy, Ahmed F. Ebrahim

FIU Electronic Theses and Dissertations

The rapid development of various power electronics applications facilitates the integration of many smart grid applications in recent years. However, integration of intermittent renewable energy sources, highly stochastic electric vehicles (EVs) activities on the grid and time-varying smart loads have increased the level of grid vulnerability to unusual and high complexity and quality-related problems. Among these problems is to accurately estimate the real contribution and consumption of household loads, in the era of smart appliances and interoperability operation, and its relative impact to the grid’s operation. Specifically, household loads represent a significant percentage of electrical energy consumption and, therefore, could …