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Frameworks To Investigate Robustness And Disease Characterization/Prediction Utility Of Time-Varying Functional Connectivity State Profiles Of The Human Brain At Rest, Anees Abrol Nov 2018

Frameworks To Investigate Robustness And Disease Characterization/Prediction Utility Of Time-Varying Functional Connectivity State Profiles Of The Human Brain At Rest, Anees Abrol

Electrical and Computer Engineering ETDs

Neuroimaging technologies aim at delineating the highly complex structural and functional organization of the human brain. In recent years, several unimodal as well as multimodal analyses of structural MRI (sMRI) and functional MRI (fMRI) neuroimaging modalities, leveraging advanced signal processing and machine learning based feature extraction algorithms, have opened new avenues in diagnosis of complex brain syndromes and neurocognitive disorders. Generically regarding these neuroimaging modalities as filtered, complimentary insights of brain’s anatomical and functional organization, multimodal data fusion efforts could enable more comprehensive mapping of brain structure and function.

Large scale functional organization of the brain is often studied by …


Brain Connectivity Networks For The Study Of Nonlinear Dynamics And Phase Synchrony In Epilepsy, Hoda Rajaei Oct 2018

Brain Connectivity Networks For The Study Of Nonlinear Dynamics And Phase Synchrony In Epilepsy, Hoda Rajaei

FIU Electronic Theses and Dissertations

Assessing complex brain activity as a function of the type of epilepsy and in the context of the 3D source of seizure onset remains a critical and challenging endeavor. In this dissertation, we tried to extract the attributes of the epileptic brain by looking at the modular interactions from scalp electroencephalography (EEG). A classification algorithm is proposed for the connectivity-based separation of interictal epileptic EEG from normal. Connectivity patterns of interictal epileptic discharges were investigated in different types of epilepsy, and the relation between patterns and the epileptogenic zone are also explored in focal epilepsy.

A nonlinear recurrence-based method is …