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Full-Text Articles in Computer Engineering

A Study Of Correlations Between The Definition And Application Of The Gene Ontology, Yuji Mo Dec 2011

A Study Of Correlations Between The Definition And Application Of The Gene Ontology, Yuji Mo

Computer and Electronics Engineering: Dissertations, Theses, and Student Research

When using the Gene Ontology (GO), nucleotide and amino acid sequences are annotated by terms in a structured and controlled vocabulary organized into relational graphs. The usage of the vocabulary (GO terms) in the annotation of these sequences may diverge from the relations defined in the ontology. We measure the consistency of the use of GO terms by comparing GO's defined structure to the terms' application. To do this, we first use synthetic data with different characteristics to understand how these characteristics influence the correlation values determined by various similarity measures. Using these results as a baseline, we found that …


Ontology For Psychophysiological Dysregulation Of Anger/Aggression, Swathi Vasanthapuram May 2011

Ontology For Psychophysiological Dysregulation Of Anger/Aggression, Swathi Vasanthapuram

Department of Computer Science and Engineering: Dissertations, Theses, and Student Research

The advancement of Information Technology in the last four decades led to the use of computers in medicine. A new area called Medical Informatics has emerged. This area comprises the application of IT to healthcare with the aim of creating tools that help healthcare personnel diagnose and treat patients more accurately and efficiently. IT not only provides tools for storing, integrating, and updating patient information base but also for processing information efficiently. One of such tools is a Clinical Decision Support System. Ontologies are an integral part of clinical decision support systems because they help formalize and integrate domain knowledge. …