Computer Engineering Commons^™

Imir: Identifying Mirna Regulation In Diseases: Bioinformatics Tool, Jeremy Yu, Bolade Ottola, Theo Contes

Capstone Design Expo Posters

Cancer mutations involves various biological factors and cellular mechanisms involving genes, miRNAs, transcription factors (TFs), chemicals etc. Hence, understanding the activity and role of all of these factors can be exploited for therapeutics. To aid this, iMir, a web portal with multi-tabbed design, analysis and user-guide has been developed to search, analyze and visualize the miRNA-disease, miRNA-TF-gene, miRNA-drug associations. Agile methodology was adopted for the software development of this tool. Weekly requirements and goals were discussed, drafted and accomplished and subject to review, testing and documentation. Code integrated upon approval. iMir has been developed using MySQL as a database and …