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Computer Engineering Commons

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Portland State University

2021

Communicable diseases -- Epidemiology -- Mathematical models

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Modeling The Effect Of The Covid-19 Pandemic On Azithromycin Prescription In General Practices Across The Uk, Oluwasegun Isaac Daramola Aug 2021

Modeling The Effect Of The Covid-19 Pandemic On Azithromycin Prescription In General Practices Across The Uk, Oluwasegun Isaac Daramola

altREU Projects

In the early months of the COVID-19 pandemic, it was reported that some antibiotics were prescribed as a remedy for viral treatment and prophylaxis based on non-randomized, uncontrolled short clinical trials. A major antibiotic consulted being Azithromycin; a broad-spectrum macrolide selected based on its immunomodulatory effects in chronic inflammatory lung diseases, with a seasonal prescription increase of 21.5% in March 2020 compared to March 2019.

To analyze the effect and possible antimicrobial resistance impact of the pandemic on Azithromycin prescription across general practices in the United Kingdom (UK), this study uses a time series decomposition modeling method to compare a …