Computer Engineering Commons^™

An Investigation Of Information Structures In Dna, Joel Mohrmann

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

The information-containing nature of the DNA molecule has been long known and observed. One technique for quantifying the relationships existing within the information contained in DNA sequences is an entity from information theory known as the average mutual information (AMI) profile. This investigation sought to use principally the AMI profile along with a few other metrics to explore the structure of the information contained in DNA sequences.

Treating DNA sequences as an information source, several computational methods were employed to model their information structure. Maximum likelihood and maximum a posteriori estimators were used to predict missing bases in DNA sequences. …

Cometrics: A New Software Tool For Behavior‑Analytic Clinicians And Machine Learning Researchers, Walker S. Arce, Seth G. Walker, Morgan L. Hurtz

Department of Electrical and Computer Engineering: Faculty Publications

Cometrics is a Microsoft Windows compatible clinical tool for the collection and recording of frequency- and duration-based target behaviors, physiological signals, and video data. This software package is designed to record in-vivo observational and physiological data. In addition, we have included features that allow observers to capture video from real-time camera feeds and import saved video for retroactive data collection. By using Microsoft Excel-based spreadsheets, also called keystroke files, assessment and treatment sessions are exported into a single document using the click of a button. Integrated interobserver agreement metrics allow comparisons across primary and reliability observers, with the output exported …

Unobtrusive Data Collection In Clinical Settings For Advanced Patient Monitoring And Machine Learning, Walker Arce

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

When applying machine learning to clinical practice, a major hurdle that will be encountered is the lack of available data. While the data collected in clinical therapies is suitable for the types of analysis that are needed to measure and track clinical outcomes, it may not be suitable for other types of analysis. For instance, video data may have poor alignment with behavioral data, making it impossible to extract the videos frames that directly correlate with the observed behavior. Alternatively, clinicians may be exploring new data modalities, such as physiological signal collection, to research methods of improving clinical outcomes that …

Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan

Department of Electrical and Computer Engineering: Faculty Publications

Coronary artery disease (CAD) is one of the major cardiovascular diseases and represents the leading causes of global mortality. Developing new diagnostic and therapeutic approaches for CAD treatment are critically needed, especially for an early accurate CAD detection and further timely intervention. In this study, we successfully isolated human plasma small extracellular vesicles (sEVs) from four stages of CAD patients, that is, healthy control, stable plaque, non-ST-elevation myocardial infarction, and ST-elevation myocardial infarction. Surface-enhanced Raman scattering (SERS) measurement in conjunction with five machine learning approaches, including Quadratic Discriminant Analysis, Support Vector Machine (SVM), K-Nearest Neighbor, Artificial Neural network, were then …

Sers Spectroscopy With Machine Learning To Analyze Human Plasma Derived Sevs For Coronary Artery Disease Diagnosis And Prognosis, Xi Huang, Bo Liu, Shenghan Guo, Weihong Guo, Ke Liao, Guoku Hu, Wen Shi, Mitchell Kuss, Michael J. Duryee, Daniel R. Anderson, Yongfeng Lu, Bin Duan

Department of Electrical and Computer Engineering: Faculty Publications

Coronary artery disease (CAD) is one of the major cardiovascular diseases and represents the leading causes of global mortality. Developing new diagnostic and therapeutic approaches for CAD treatment are critically needed, especially for an early accurate CAD detection and further timely intervention. In this study, we successfully isolated human plasma small extracellular vesicles (sEVs) from four stages of CAD patients, that is, healthy control, stable plaque, non-ST-elevation myocardial infarction, and ST-elevation myocardial infarction. Surface-enhanced Raman scattering (SERS) measurement in conjunction with five machine learning approaches, including Quadratic Discriminant Analysis, Support Vector Machine (SVM), K-Nearest Neighbor, Artificial Neural network, were then …

Bibliometric Review On Image Based Plant Phenotyping, Shrikrishna Ulhas Kolhar, Jayant Jagtap

Library Philosophy and Practice (e-journal)

Plant phenotyping is a quantitative description of structural, physiological and temporal traits of plants resulting from interaction of plant genotypes with the environment. A rapid development is in progress in the field of image-based plant phenotyping. Plant phenotyping has wide range of applications in plant breeding research, plant growth prediction, biotic and abiotic stress analysis, crop management and early disease detection. The main motive is to provide detailed bibliometric review in order to know the available literature and current research trends in the area of plant phenotyping using plant images. The bibliometric analysis is primarily based on Scopus, web of …

Pixel-Level Deep Multi-Dimensional Embeddings For Homogeneous Multiple Object Tracking, Mateusz Mittek

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

The goal of Multiple Object Tracking (MOT) is to locate multiple objects and keep track of their individual identities and trajectories given a sequence of (video) frames. A popular approach to MOT is tracking by detection consisting of two processing components: detection (identification of objects of interest in individual frames) and data association (connecting data from multiple frames). This work addresses the detection component by introducing a method based on semantic instance segmentation, i.e., assigning labels to all visible pixels such that they are unique among different instances. Modern tracking methods often built around Convolutional Neural Networks (CNNs) and additional, …

Design Of A Distributed Real-Time E-Health Cyber Ecosystem With Collective Actions: Diagnosis, Dynamic Queueing, And Decision Making, Yanlin Zhou

Department of Electrical and Computer Engineering: Dissertations, Theses, and Student Research

In this thesis, we develop a framework for E-health Cyber Ecosystems, and look into different involved actors. The three interested parties in the ecosystem including patients, doctors, and healthcare providers are discussed in 3 different phases. In Phase 1, machine-learning based modeling and simulation analysis is performed to remotely predict a patient's risk level of having heart diseases in real time. In Phase 2, an online dynamic queueing model is devised to pair doctors with patients having high risk levels (diagnosed in Phase 1) to confirm the risk, and provide help. In Phase 3, a decision making paradigm is proposed …