Computer Engineering Commons^™

A Machine Learning Framework For Identifying Molecular Biomarkers From Transcriptomic Cancer Data, Md Abdullah Al Mamun

FIU Electronic Theses and Dissertations

Cancer is a complex molecular process due to abnormal changes in the genome, such as mutation and copy number variation, and epigenetic aberrations such as dysregulations of long non-coding RNA (lncRNA). These abnormal changes are reflected in transcriptome by turning oncogenes on and tumor suppressor genes off, which are considered cancer biomarkers.

However, transcriptomic data is high dimensional, and finding the best subset of genes (features) related to causing cancer is computationally challenging and expensive. Thus, developing a feature selection framework to discover molecular biomarkers for cancer is critical.

Traditional approaches for biomarker discovery calculate the fold change for each …

A Statistical-Mining Techniques’ Collaboration For Minimizing Dimensionality In Ovarian Cancer Data, Mohamed Attia, Maha Farghaly, Mohamed Hamada, Amira M. Idrees Ami

Future Computing and Informatics Journal

A feature is a single measurable criterion to an observation of a process. While knowledge discovery techniques successfully contribute in many fields, however, the extensive required data processing could hinder the performance of these techniques. One of the main issues in processing data is the dimensionality of the data. Therefore, focusing on reducing the data dimensionality through eliminating the insignificant attributes could be considered one of the successful steps for raising the applied techniques’ performance. On the other hand, focusing on the applied field, ovarian cancer patients continuously suffer from the extensive analysis requirements for detecting the disease as well …

Review Of Data Mining Techniques For Detecting Churners In The Telecommunication Industry, Mahmoud Ewieda, Mohamed Ismail Roushdy, Essam Shaaban

Future Computing and Informatics Journal

The telecommunication sector has been developed rapidly and with large amounts of data obtained as a result of increasing in the number of subscribers, modern techniques, data-based applications, and services. As well as better awareness of customer requirements and excellent quality that meets their satisfaction. This satisfaction raises rivalry between firms to maintain the quality of their services and upgrade them. These data can be helpfully extracted for analysis and used for predicting churners. Researchers around the world have conducted important research to understand the uses of Data mining (DM) that can be used to predict customers' churn. This …

A Scale Space Local Binary Pattern (Sslbp) – Based Feature Extraction Framework To Detect Bones From Knee Mri Scans, Jinyeong Mun

Electronic Theses and Dissertations

The medical industry is currently working on a fully autonomous surgical system, which is considered a novel modality to go beyond technical limitations of conventional surgery. In order to apply an autonomous surgical system to knees, one of the primarily responsible areas for supporting the total weight of human body, accurate segmentation of bones from knee Magnetic Resonance Imaging (MRI) scans plays a crucial role. In this paper, we propose employing the Scale Space Local Binary Pattern (SSLBP) feature extraction, a variant of local binary pattern extractions, for detecting bones from knee images. The proposed methods consist of two phases. …

Breast Cancer Classification Of Mammographic Masses Using Circularity Max Metric, A New Method, Tae Keun Heo

Electronic Theses and Dissertations

Breast cancer classification can be divided into two categories. The first category is a benign tumor, and the other is a malignant tumor. The main purpose of breast cancer classification is to classify abnormalities into benign or malignant classes and thus help physicians with further analysis by minimizing potential errors that can be made by fatigued or inexperienced physicians. This paper proposes a new shape metric based on the area ratio of a circle to classify mammographic images into benign and malignant class. Support Vector Machine is used as a machine learning tool for training and classification purposes. The improved …