Computer Engineering Commons^™

Identifying And Minimizing Underspecification In Breast Cancer Subtyping, Jonathan Cheuk-Kiu Tang

Master's Theses

In the realm of biomedical technology, both accuracy and consistency are crucial to the development and deployment of these tools. While accuracy is easy to measure, consistency metrics are not so simple to measure, especially in the scope of biomedicine where prediction consistency can be difficult to achieve. Typically, biomedical datasets contain a significantly larger amount of features compared to the amount of samples, which goes against ordinary data mining practices. As a result, predictive models may fail to find valid pathways for prediction during training on such datasets. This concept is known as underspecification.

Underspecification has been more accepted …

Applied Hw/Sw Co-Design: Using The Kendall Tau Algorithm For Adaptive Pacing, Kenneth W. Chee

Master's Theses

Microcontrollers, the brains of embedded systems, have found their way into every aspect of our lives including medical devices such as pacemakers. Pacemakers provide life supporting functions to people therefore it is critical for these devices to meet their timing constraints. This thesis examines the use of hardware co-processing to accelerate the calculation time associated with the critical tasks of a pacemaker. In particular, we use an FPGA to accelerate a microcontroller’s calculation time of the Kendall Tau Rank Correlation Coefficient algorithm. The Kendall Tau Rank Correlation Coefficient is a statistical measure that determines the pacemaker’s voltage level for heart …

Universal Engineering Programmer – An In-House Development Tool For Developing And Testing Implantable Medical Devices In St. Jude Medical, Khoa Tat Do

Master's Theses

During development and testing of the functionality of the pacemaker and defibrillator device, engineers in the St. Jude Medical Cardiac Rhythm Management Division use an in-house development tool called Universal Engineering Programmer (UEP) to ensure the device functions as expected, before it can be used to test on an animal or a human during the implantation process. In addition, some applications of UEP are incorporated into the official releases of the device product. UEP has been developed and used by engineers across departments in the St. Jude Medical Cardiac Rhythm Management Division (CRMD). This thesis covers the flexible and reusable …