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Full-Text Articles in Computational Engineering
Modeling Of Swimming Cells From Nano-Scale To Micro-Scale, Yicheng Zhao
Modeling Of Swimming Cells From Nano-Scale To Micro-Scale, Yicheng Zhao
McKelvey School of Engineering Theses & Dissertations
Certain human genetic diseases -- primary ciliary dyskinesia, infertility, and hydrocephalus -- are characterized by changes in beat frequency and waveform of cilia and flagella. Chlamydomonas reinhardtii, which is a single-cell green alga about ten micrometers in diameter that swims with two flagella, serves as an excellent biological model because its flagella share the same structure and genetic background as mammalian cilia and flagella. This study uses the finite element method to investigate the behavior of C. reinhardtii swimming from nano-scale to micro-scale. At the device-level, micro-scale modeling indicates that well-designed acoustic microfluidic devices can be used to trap groups …
Optimization Of Blalock-Taussig Shunt And Anastomotic Geometry For Vascular Access Fistula Using A Genetic Algorithm, Guangyu Bao
Optimization Of Blalock-Taussig Shunt And Anastomotic Geometry For Vascular Access Fistula Using A Genetic Algorithm, Guangyu Bao
McKelvey School of Engineering Theses & Dissertations
Blalock-Taussig (BT) shunts are used for defects that affect the flow of blood from the right ventricle, through the pulmonary artery, and to the lungs. Arteriovenous (AV) fistula is one type of vascular access which is a surgically created vein used to remove and return blood during hemodialysis. Plastic grafts used in the above two reconstructions may result in areas of non-physiologic flow in the grafts leading to risk of stenosis (blocked area) and thrombosis, which is the single major cause for access morbidity. The focus of this thesis is to study BT shunts and anastomoses models using Computational Fluid …